sickness absence due to specific mental diagnoses and all-cause and cause-specific mortality a cohort study of 4.9 million inhabitants of sweden病假因特定的心理诊断和全因死亡率和特殊瑞典490万居民的队列研究.pdfVIP
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sickness absence due to specific mental diagnoses and all-cause and cause-specific mortality a cohort study of 4.9 million inhabitants of sweden病假因特定的心理诊断和全因死亡率和特殊瑞典490万居民的队列研究
Sickness Absence Due to Specific Mental Diagnoses and
All-Cause and Cause-Specific Mortality: A Cohort Study
of 4.9 Million Inhabitants of Sweden
1 ˚ 1 2 3 4
Ellenor Mittendorfer-Rutz *, Linnea Kjeldgard , Bo Runeson , Aleksander Perski , Maria Melchior ,
Jenny Head5, Kristina Alexanderson1
1 Department of Clinical Neuroscience, Division of Insurance Medicine, Karolinska Institutet, Stockholm, Sweden, 2 Department of Clinical Neuroscience, Centre for
Psychiatric Research, Karolinska Institutet, Stockholm, Sweden, 3 Stress Research Institute, Stockholm University, Stockholm, Sweden, 4 INSERM, Villejuif, France,
5 Department of Epidemiology and Public Health, University College London, London, United Kingdom
Abstract
Background: Despite the magnitude and increase of sickness absence due to mental diagnoses, little is known regarding
long-term health outcomes. The aim of this nationwide population-based, prospective cohort study was to investigate the
association between sickness absence due to specific mental diagnoses and the risk of all-cause and cause-specific
mortality.
Methods: A cohort of all 4 857 943 individuals living in Sweden on 31.12.2004 (aged 16–64 years, not sickness absent, or on
retirement or disability pension), was followed from 01.01.2005 through 31.12.2008 for all-cause and cause-specific mortality
(suicide, cancer, circulatory disease) through linkage of individual register data. Individuals with at least one new sick-leave
spell with a mental diagnosis in 2005 were compared to individuals with no sickness absence. Hazard ratios (HR) and 95%
confidence intervals (CI) were estimated by Cox regression, adjusting for age,
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