signal regulatory protein α (sirpα)+ cells in the adaptive response to esat-6cfp-10 protein of tuberculous mycobacteria信号调节蛋白α(sirpα)+细胞的适应性反应esat-6cfp-10结核分枝杆菌的蛋白质.pdfVIP

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signal regulatory protein α (sirpα)+ cells in the adaptive response to esat-6cfp-10 protein of tuberculous mycobacteria信号调节蛋白α(sirpα)+细胞的适应性反应esat-6cfp-10结核分枝杆菌的蛋白质.pdf

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signalregulatoryproteinα(sirpα)cellsintheadaptiveresponsetoesat-6cfp-10proteinoftuberculousmycobacteria信号调节蛋白α(sirpα)细胞的适应性反应esat-6cfp-10结核分枝杆菌的蛋白质

Signal Regulatory Protein a (SIRPa)+ Cells in the Adaptive Response to ESAT-6/CFP-10 Protein of Tuberculous Mycobacteria 1 1 1 1 2 W. Ray Waters *, Mitchell V. Palmer , Brian J. Nonnecke , Tyler C. Thacker , D. Mark Estes , Michelle H. 3 3 4 5 6 Larsen , William R. Jacobs Jr , Peter Andersen , James McNair , F. C. Minion , Konstantin P. 7 8 8 1 Lyashchenko , R. Glyn Hewinson , H. Martin Vordermeier , Randy E. Sacco 1 National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa, United States of America, 2 University of Texas Medical Branch, Department of Pediatrics and the Sealy Center for Vaccine Development, Galveston, Texas, United States of America, 3 Howard Hughes Medical Institute and Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America, 4 Statens Serum Institute, Copenhagen, Denmark, 5 Bacteriology Department, Veterinary Sciences Division, Stormont, Belfast, 6 Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, United States of America, 7 Chembio Diagnostic Systems, Medford, New York, United States of America, 8 UK Veterinary Laboratories Agency, Weybridge, New Haw, Addlestone, Surrey, United Kingdom Abstract Background: Early secretory antigenic target-6 (ESAT-6) and culture filtrate protein-10 (CFP-10) are co-secreted proteins of Mycobacterium tuberculosis complex mycobacteria (includes M. bovis, the zoonotic agent of bovine tuberculosis) involved in