simulated epidemics in an empirical spatiotemporal network of 50,185 sexual contacts模拟50185年实证时空网络流行的性接触.pdfVIP

Simulated Epidemics in an Empirical Spatiotemporal Network of 50,185 Sexual Contacts 1 2 1,3 Luis E. C. Rocha *, Fredrik Liljeros , Petter Holme ˚ ˚ 1 IceLab, Department of Physics, Umea University, Umea, Sweden, 2 Department of Sociology, Stockholm University, Stockholm, Sweden, 3 Department of Energy Science, Sungkyunkwan University, Suwon, Korea Abstract Sexual contact patterns, both in their temporal and network structure, can influence the spread of sexually transmitted infections (STI). Most previous literature has focused on effects of network topology; few studies have addressed the role of temporal structure. We simulate disease spread using SI and SIR models on an empirical temporal network of sexual contacts in high-end prostitution. We compare these results with several other approaches, including randomization of the data, classic mean-field approaches, and static network simulations. We observe that epidemic dynamics in this contact structure have well-defined, rather high epidemic thresholds. Temporal effects create a broad distribution of outbreak sizes, even if the per-contact transmission probability is taken to its hypothetical maximum of 100%. In general, we conclude that the temporal correlations of our network accelerate outbreaks, especially in the early phase of the epidemics, while the network topology (apart from the contact-rate distribution) slows them down. We find that the temporal correlations of sexual contacts can significantly change simulated outbreaks in a large empirical sexual network. Thus, temporal structures are needed alongside network topology to fully understand the spread of STIs. On a side note, our simulations further sugges