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常用的降血脂药品以及使用(Commonly used lipid-lowering drugs and use)
常用的降血脂药品以及使用(Commonly used lipid-lowering drugs and use)
What are the commonly used hypolipidemic drugs?
Blood fat mainly refers to the plasma cholesterol and triglyceride. When cholesterol is higher than 7.0mmol / L, triglyceride is higher than 1.8mmo1 / L, it is called hyperlipidemia. Increased blood lipids are closely related to atherosclerosis, hypertension, cardiovascular and cerebrovascular diseases, and more and more attention has been paid to it.
Increased blood lipids can be divided into three types. Simple hypertriglyceridemia is characterized by increased triglyceride and normal or slightly elevated cholesterol. Simple hypercholesterolemia is characterized by marked increase in cholesterol and normal triglyceride. Mixed type hyperlipidemia, cholesterol and triglyceride are increased. When using lipid-lowering drugs, drugs should be selected according to different types of hyperlipidemia.
(1) clofibrate: generic clofibrate, the triglyceride decreased by about 23%, no obvious effect on cholesterol, down about 6%, usage: every 0.25 to 0.5 grams, daily 3 ~ 4 times oral. The medicine has fibrinolysis and can cause gallstone disease when taken for a long time. The side effects include nausea, diarrhea, arthralgia, liver and kidney dysfunction and pregnancy and lactation.
(2) niacin: mainly reduce triglycerides (about 26%), long-term use can also reduce cholesterol (about 10%), while expanding the role of peripheral blood vessels, medication can reduce the incidence of myocardial infarction. Take 3 to 1 grams each time, 0.5 times a day. After taking, often have skin flushing, itching, gastrointestinal reaction, after withdrawal may disappear.
(3) chondroitin sulfate: also known as Kang real, can reduce the arterial wall and the decrease of blood lipid lipoprotein uptake. It also has anti coagulation, anti-inflammatory, anti thrombosis and promote collateral circulation, and can be used to control crown, heart, japonica and so on. Take 0.3 to 0.6 grams each time.
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