老年下肢动脉硬化闭塞症（Senile arteriosclerotic occlusive disease of lower extremity）.docVIP

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老年下肢动脉硬化闭塞症（Senile arteriosclerotic occlusive disease of lower extremity）.doc

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老年下肢动脉硬化闭塞症（Senile arteriosclerotic occlusive disease of lower extremity）

老年下肢动脉硬化闭塞症（Senile arteriosclerotic occlusive disease of lower extremity） With the changes in the dietary structure (including increased intake of fatty foods), an increase in life expectancy, and improvements in diagnostic techniques, there is an increasing trend in the number of patients diagnosed with lower extremity arteriosclerosis obliterans. Shanghai Zhongshan Hospital from May 1963 to May 1988 has treated 100 cases of lower extremity arteriosclerosis obliterans, in 60s for 3 cases, 23 cases in 70s, 74 cases in 80s (nearly 3 years, 30 cases). Arteriosclerosis obliterans is a chronic arterial occlusive disease caused by atherosclerotic lesions of the arteries. It mainly invades the large and medium-sized arteries of the lower abdominal aorta, iliac artery, femoral artery and so on. Because of atherosclerotic plaques, secondary degeneration of the arteries and secondary thrombosis, the formation of luminal occlusion gradually leads to ischemia in the lower extremities. The main clinical manifestations were chills, numbness, pain, intermittent claudication, arterial pulsation disappeared, limb tissue malnutrition and ulcers or gangrene of toes or feet. [pathogeny] The blood total cholesterol, triglyceride three and beta lipoprotein in patients with arteriosclerosis obliterans are higher than normal, especially in recent years Lipoprotein decreased and low density lipoprotein increased, suggesting that lipid metabolism disorder is closely related to the occurrence and development of this disease. In addition, diabetic patients suffer from arteriosclerosis obliterans more than those without diabetes, and lead to early onset of atherosclerosis and a serious degree. Some people believe that the increase in blood coagulation can aggravate atherosclerotic occlusion. There is also a statistical point of view that smoking is associated with the occurrence and progression of atherosclerotic occlusion. [pathology] Atherosclerotic occlusion is common in the lower end of th