25th annual san antonio breast cancer symposium, san antonio, texas, usa, 10–14 december 2002 update on preclinical and translational research25日年度圣安东尼奥乳腺癌研讨会上,圣安东尼奥,德克萨斯州,美国,2002年12月10 - 14更新临床和转化研究.pdfVIP

25th annual san antonio breast cancer symposium, san antonio, texas, usa, 10–14 december 2002 update on preclinical and translational research25日年度圣安东尼奥乳腺癌研讨会上,圣安东尼奥,德克萨斯州,美国,2002年12月10 - 14更新临床和转化研究.pdf

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25th annual san antonio breast cancer symposium, san antonio, texas, usa, 10–14 december 2002 update on preclinical and translational research25日年度圣安东尼奥乳腺癌研讨会上,圣安东尼奥,德克萨斯州,美国,2002年12月10 - 14更新临床和转化研究

Available online /content/5/2/109 Meeting report 25th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 10–14 December 2002 Update on preclinical and translational research Julia E Head1 and Alistair Ring2 1Section of Medicine, Institute of Cancer Research, Sutton, UK 2Department of Academic Biochemistry, Royal Marsden Hospital, London, UK Corresponding author: Julia E Head (e-mail: jhead@icr.ac.uk) Received: 8 January 2003 Accepted: 15 January 2003 Published: 5 February 2003 Breast Cancer Res 2003, 5:109-112 (DOI 10.1186/bcr575) © 2003 BioMed Central Ltd (Print ISSN 1465-5411; Online ISSN 1465-542X) See clinical report, page 113 Abstract The Annual San Antonio Breast Cancer Symposium is one of the largest regular conferences devoted to breast cancer research and treatment. In particular, it provides a forum in which to discuss the more translational aspects of current basic research, and the 2002 meeting was no exception. Growth factor pathways and endocrine resistance, cancer genomics and the clinical applications of proteomics were three of the major topics for discussion. Presentations on genetic susceptibility and the development of prognostic and predictive markers also created much interest. Keywords: BRCA 1/2, cDNA microarray, growth factor pathways, prognostic and predictive markers, proteomics Introduction Growth factor pathways and signalling The 25th Annual San Antonio Breast Cancer Symposium Elucidation of the signal transduction cascade down- attracted nearly 5000 physicians and researchers in stream from growth factors and receptor tyrosine kinases breast oncology, as

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