普萘洛尔、速尿治疗晚期肝癌及肝转移癌合并腹水观察.docVIP

普萘洛尔、速尿治疗晚期肝癌及肝转移癌合并腹水观察 　 ; 作者：李莹，黎苗，翟艳辉，关展鸿 毕业论文 【关键词】; 晚期肝癌；肝转移癌；腹水；普萘洛尔；速尿 毕业论文 　　　［摘要］; 目的; 晚期肝癌及肝转移癌多并发腹水，治疗较困难。笔者在抗癌，纠正水、电解质紊乱及低蛋白血症的基础上，观察普萘洛尔、速尿治疗的效果。方法; 54例病人常规检查，排除心脏疾病后，给予口服普萘洛尔10 mg，3次/d；速尿20 mg，3次/d。每天测量腹围、记录尿量，定期检查水、电解质，适量补充钾，纠正低蛋白血症。连用1周，有效后继续使用至1个月，无效者停用。结果; 54例病人中好转12例，有效26例，显效8例，无效8例，总有效率85.2%。结论; 普萘洛尔、速尿联合治疗晚期肝癌及肝转移癌并发腹水，可降低门静脉高压，减轻腹水，且无特殊副作用，值得继续研究。 毕业论文 　　［关键词］; 晚期肝癌；肝转移癌；腹水；普萘洛尔；速尿 毕业论文 　　Propranolo and furosemide in treatment of advanced hepatocarcinoma and meta static carcinoma with ascites 毕业论文 　　［Abstract］; Objective; Its difficult to treat the ascites in hepatocarcinoma or liver metastatic carcinoma patients.We observed the circumstance of ascites of 54 hepatocarcinoma or liver metastatic carcinoma patients，who received propranolol and furosemide besides anticancer therapy，rectifying the abnormal electrolyte and hypoproteinemia，and obtained the good effect.Methods; 54 patients without cardiovascular diseases were given propranolol at the dose of 10mg every time，3 times per day and furosemide at the dose of 20mg every time，3 times per day for a week.Measuring abdominal perimeter and recording the urine volume everyday，checking electrolyte balance periodically，and coming it back，and rectifying hypoproteinemia.The prescription was administered sequentially if effective，or stopped.Results; 54 patients were evaluable for response.The overall response rate was 85.2%( 12 patients were improvement，26 were effective and 8 were valid ).8 patients were no response.Conclusion; Propranolol with furosemide combination is effective to depress high pressure of portalis and erupt the ascites.and welltolerated in hepatocarcinoma or liver metastatic carcinoma patients.So it is worthy to be further studied. 毕业论文 　　［Key words］; advanced hepatocarcinoma；liver metastatic carcinoma；ascites；propranolol；furosemide 毕业论文 　　晚期肝癌及肝转移癌多合并腹水，治疗十分棘手，病人也很痛苦，生活质量低下。近几年来我们试用普萘洛尔加速尿治疗晚期肝癌及肝转移癌合并腹水病人54例，减轻了症状，改善了患者的生活质量，取得了较好的效果，现总结如下。 毕业论文 　　1; 资料与方法