an in vitro study comparing a peripherally inserted central catheter to a conventional central venous catheter no difference in static and dynamic pressure transmission体外研究比较次要地插入中央导管传统中央静脉导管在静态和动态压力传播没有区别.pdfVIP

an in vitro study comparing a peripherally inserted central catheter to a conventional central venous catheter no difference in static and dynamic pressure transmission体外研究比较次要地插入中央导管传统中央静脉导管在静态和动态压力传播没有区别.pdf

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an in vitro study comparing a peripherally inserted central catheter to a conventional central venous catheter no difference in static and dynamic pressure transmission体外研究比较次要地插入中央导管传统中央静脉导管在静态和动态压力传播没有区别

Latham et al. BMC Anesthesiology 2010, 10:18 /1471-2253/10/18 RESEARCH ARTICLE Open Access An in vitro study comparing a peripherally inserted central catheter to a conventional central venous catheter: no difference in static and dynamic pressure transmission Heath E Latham1,3*, Timothy T Dwyer1,3, Bethene L Gregg2,3, Steven Q Simpson1,3 Abstract Background: Early goal directed therapy improves survival in patients with septic shock. Central venous pressure (CVP) monitoring is essential to guide adequate resuscitation. Use of peripherally inserted central catheters (PICC) is increasing, but little data exists comparing a PICC to a conventional CVP catheter. We studied the accuracy of a novel PICC to transmit static and dynamic pressures in vitro. Methods: We designed a device to generate controlled pressures via a column of water allowing simultaneous measurements from a PICC and a standard triple lumen catheter. Digital transducers were used to obtain all pressure readings. Measurements of static pressures over a physiologic range were recorded using 5Fr and 6Fr dual lumen PICCs. Additionally, random repetitive pressure pulses were applied to the column of water to simulate physiologic intravascular pressure variations. The resultant PICC and control waveforms were recorded simultaneously. Results: Six-hundred thirty measurements were made using the 5 Fr and 6 Fr PICCs. The average bias determined by Bland-Altman plot was 0.043 mmHg for 5 Fr PICC and 0.023 mmHg for 6 Fr PICC with a difference range of 1.0 to -1.0. The correlation coefficient for both catheters was 1.0 (p-value 0.001). Dynamic pressure waveforms plotted simultaneously between PICC and control revealed equal peaks and troughs. Conclusion: In vitro, no static or dynamic pressure differences were found between the PICC and a conventional CVP ca

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