analysis of antimicrobial susceptibility and virulence factors in helicobacter pylori clinical isolates分析抗菌药物敏感性和幽门螺旋杆菌临床分离株的毒力因素.pdfVIP
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analysis of antimicrobial susceptibility and virulence factors in helicobacter pylori clinical isolates分析抗菌药物敏感性和幽门螺旋杆菌临床分离株的毒力因素
BMC Gastroenterology BioMed Central
Research article Open Access
Analysis of antimicrobial susceptibility and virulence factors in
Helicobacter pylori clinical isolates
Anita Paula Ortiz Godoy, Marcelo Lima Ribeiro, Yune Helena
Borges Benvengo, Lea Vitiello, Maira de Carvalho Bueno Miranda,
Sergio Mendonça and José Pedrazzoli Jr*
Address: Clinical Pharmacology and Gastroenterology Unit, São Francisco University Medical School, Bragança Paulista, SP, Brazil
Email: Anita Paula Ortiz Godoy - anita@.br; Marcelo Lima Ribeiro - marceloribeiro@.br; Yune Helena
Borges Benvengo - yune@.br; Lea Vitiello - lea@.br; Maira de
Carvalho Bueno Miranda - maira@.br; Sergio Mendonça - sergiomendonca@.br;
José Pedrazzoli* - pedrazzoli@.br
* Corresponding author
Published: 11 August 2003 Received: 17 June 2003
Accepted: 11 August 2003
BMC Gastroenterology 2003, 3:20
This article is available from: /1471-230X/3/20
© 2003 Godoy et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all
media for any purpose, provided this notice is preserved along with the articles original URL.
Abstract
Background: In this study, we evaluated the prevalence of primary resistance of Brazilian H. pylori
isolates to metronidazole, clarithromycin, amoxicillin, tetracycline, and furazolidone. In addition,
the vacA, iceA, cagA and cagE genotypes of strains isolated from Brazilian patients were determined
and associated with clinical data in an effort to correlate these four
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