原创力文档hormone replacement therapy in rheumatoid arthritis is associated with lower serum levels of soluble il-6 receptor and higher insulin-like growth factor 1激素替代治疗类风湿性关节炎与低血清可溶性白介素受体水平和高胰岛素样生长因子1.pdfVIP
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hormone replacement therapy in rheumatoid arthritis is associated with lower serum levels of soluble il-6 receptor and higher insulin-like growth factor 1激素替代治疗类风湿性关节炎与低血清可溶性白介素受体水平和高胰岛素样生长因子1
Arthritis Research Therapy Vol 5 No 4 Forsblad d’Elia et al.
Research article Open Access
Hormone replacement therapy in rheumatoid arthritis is
associated with lower serum levels of soluble IL-6 receptor and
higher insulin-like growth factor 1
1 2 3 1
Helena Forsblad d’Elia Lars-Åke Mattsson , Claes Ohlsson , Elisabeth Nordborg and
Hans Carlsten1
1Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Göteborg University, Göteborg, Sweden
2Department of Obstetrics and Gynecology, The Sahlgrenska Academy at Göteborg University, Göteborg, Sweden
3Department of Internal Medicine, The Sahlgrenska Academy at Göteborg University, Göteborg, Sweden
Correspondence: Helena Forsblad d’Elia (e-mail: helena.forsblad@rheuma.gu.se)
Received: 18 Oct 2002 Revisions requested: 5 Dec 2002 Revisions received: 12 Mar 2003 Accepted: 21 Mar 2003 Published: 1 May 2003
Arthritis Res Ther 2003, 5:R202-R209 (DOI 10.1186/ar761)
© 2003 Forsblad d’Elia et al., licensee BioMed Central Ltd (Print ISSN 1478-6354; Online ISSN 1478-6362). This is an Open Access article:
verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the
articles original URL.
Abstract
Hormone replacement therapy (HRT) modulates the imbalance in levels of soluble IL-6 receptor (sIL-6R) (P0.05), which is known
bone remodeling, thereby decreasing bone loss. Sex hormones to enhance the biolog
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