interleukin-4 and 13 concentrations in infants at risk to develop bronchopulmonary dysplasiainterleukin-4浓度和13在婴儿的风险开发支气管肺的发育不良.pdfVIP
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interleukin-4 and 13 concentrations in infants at risk to develop bronchopulmonary dysplasiainterleukin-4浓度和13在婴儿的风险开发支气管肺的发育不良
BMC Pediatrics BioMed Central
Research article Open Access
Interleukin-4 and 13 concentrations in infants at risk to develop
Bronchopulmonary Dysplasia
1 2 1
R John Baier* , John Loggins and Thomas E Kruger
Address: 1Department of Pediatrics Louisiana State University Health Sciences Center 1501 Kings Highway Shreveport, Louisiana 71130-3932,
USA and 2Louisiana State University Health Sciences Center 1501 Kings Highway, Shreveport, Louisiana 71130-3932, USA
Email: R John Baier* - jbaier@; John Loggins - jloggi@; Thomas E Kruger - dkruger1@
* Corresponding author
Published: 18 August 2003 Received: 28 March 2003
Accepted: 18 August 2003
BMC Pediatrics 2003, 3:8
This article is available from: /1471-2431/3/8
© 2003 Baier et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all
media for any purpose, provided this notice is preserved along with the articles original URL.
Abstract
Background: An exaggerated inflammatory response occurs in the first few days of life in infants
who subsequently develop bronchopulmonary dysplasia (BPD). The increase of inflammatory
cytokines in many disease processes is generally balanced by a rise in anti-inflammatory cytokines.
Interleukin-4 (IL-4) and interleukin-13 (IL-13) have been shown to inhibit production of several
inflammatory cytokines important in the development of BPD.
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