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monitoring and oversight in critical care research监测和监督在急救护理研究
Available online /content/8/6/403
Commentary
Monitoring and oversight in critical care research
1 2 3
James V Lavery , Marleen LP Van Laethem and Arthur S Slutsky
1Research Scientist, Centre for Global Health Research and Inner City Health Research Unit, St. Michael’s Hospital, and Assistant Professor,
Department of Public Health Sciences and Joint Centre for Bioethics, University of Toronto, Toronto, Canada
2Research Ethics Monitor, St. Michael’s Hospital, Toronto, Canada
3Vice President, Research, St. Michael’s Hospital, and Division Director, Interdepartmental Division of Critical Care Medicine, Professor of Medicine,
Surgery and Biomedical Engineering, University of Toronto, Toronto, Canada
Correspondence: James V Lavery, laveryj@smh.toronto.on.ca
Published online: 28 September 2004 Critical Care 2004, 8:403-405 (DOI 10.1186/cc2964)
This article is online at /content/8/6/403
© 2004 BioMed Central Ltd
Abstract
Institutionally based research ethics review is a form of peer review that has – for better or worse –
become the norm throughout the world. The vast majority of research ethics review takes the form of
protocol review alone, conducted in advance of the research. Although oversight and monitoring in
clinical research have long been recognized as essential features of sound research ethics, they are
seldom exercised in ways that fulfill their motivating goals: to ensure that research is conducted as
planned; that research participants comprehend the information presented to them in the consent
process; and that the potential benefits and risks of study participation remain acc
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