neglschisandrins a-b two new dibenzocyclooctene lignans from schisandra neglecta从五味子neglecta neglschisandrins a - b两个新的dibenzocyclooctene木酚素.pdfVIP
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neglschisandrins a-b two new dibenzocyclooctene lignans from schisandra neglecta从五味子neglecta neglschisandrins a - b两个新的dibenzocyclooctene木酚素
Molecules 2008, 13, 548-555
molecules
ISSN 1420-3049
© 2008 by MDPI
/molecules
Full Paper
Neglschisandrins A-B: Two New Dibenzocyclooctene Lignans
from Schisandra neglecta
Min Chen 1,*, Xiumei Xu 2,3, Zhihua Liao 2, Li Dong 2, Lei Li 2 and Chengzhi Huang 4
1 School of Pharmacy, Key Laboratory of Eco-environments in Three Gorges Reservoir Region
(Ministry of Education), Southwest University, Chongqing 400715, P.R. China
2 Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education),
School of Life Sciences, Southwest China Normal University S Chongqing 400715, P.R. China;
E-mails: xxmei515@163.com (Xu); zhliao@ (Liao); gsnhdl@ (Dong);
leilei16@ (Li)
3 School of Life Sciences, Linyi Normal University, Linyi, Shandong Province, 276005, P.R. China
4 CQKL-LRTA, School of Pharmacy, Southwest University, Chongqing 400715, P.R. China;
E-mail: chengzhi@
* Author to whom correspondence should be addressed; E-mail: mminchen@; Phone:
(+86)2368251225; Fax: (+86
Received: 30 January 2008; in revised form: 28 February 2008 / Accepted: 29 February 2008 /
Published: 3 March 2008
Abstract: Two new dibenzocyclooctene lignans, neglschisandrins A-B (1-2), were isolated
from the stems of Schisandra neglecta. Their structures and stereochemistries were
elucidated by spectroscopic methods, including 1D- and 2D-NMR and HR-ESI-MS
techniques.
Keywords: Schisandra neglecta, dibenzocyclooctene lignans, neglschisandrins A-B.
Introduction
The stems or fruits of plants in the Schisandraceae family are widely u
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