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networks for all网络为所有
Meeting report
NNeettwwoorrkkss ffoorr aallll
Sebastian E Ahnert* and Sarah A Teichmann†
Addresses: *Theory of Condensed Matter Group, Cavendish Laboratory, University of Cambridge, JJ Thomson Avenue, Cambridge,
CB3 0HE, UK. †MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.
Correspondence: Sebastian E Ahnert. Email: sea31@hermes.cam.ac.uk
Published: 27 October 2008
Genome BBiioollooggyy 2008, 99::324 (doi:10.1186/gb-2008-9-10-324)
The electronic version of this article is the complete one and can be
found online at /2008/9/10/324
© 2008 BioMed Central Ltd
time-course data with gene-expression profiles, including
A report on the Cold Spring Harbor Laboratory/Wellcome data from transcription factor mutants. This analysis
Trust conference on Network Biology, Hinxton, UK, 27-31 revealed more complex combinatorial relationships than
August 2008. expected, including evidence for differential cis-regulatory
module occupancy depending on different threshold concen-
trations at various stages of fly development.
As molecular biology is driven by interactions between
proteins, DNA and RNA, networks are a natural way to repre- Because of post-transcriptional effects, mRNA levels can be
sent these systems. A recent network biology meeting in a poor indicator of transcription factor activity. Harman
Hinxton was attended by scientists working on transcription Bussemaker (
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