new constituents from the rhizomes of egyptian iris germanica l.新选民从埃及的根状茎虹膜蠊l。.pdfVIP

Molecules 2012, 17, 2587-2598; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article New Constituents from the Rhizomes of Egyptian Iris germanica L. Sabrin R. M. Ibrahim 1, Gamal A. Mohamed 2,† and Nawal M. Al-Musayeib 3,* 1 Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt 2 Department of Natural products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 211589, Saudi Arabia 3 Department of Pharmacognosy, Faculty of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia † Permanent address: Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut 71524, Egypt * Author to whom correspondence should be addressed; E-Mail: nalmusayeib@.sa; Tel.: +966-1291-5203 ext. 281; Fax: +966-228-2584. Received: 5 February 2012; in revised form: 23 February 2012 / Accepted: 28 February 2012 / Published: 2 March 2012 Abstract: Chemical investigation of the methanolic extract of the rhizomes of Iris germanica L. (Iridaceae) afforded two new compounds; irigenin S (7) and iriside A (12), together with ten known compounds: stigmasterol (1), -irone (2), γ-irone (3), 3-hydroxy-5-methoxyacetophenone (4), irilone (5), irisolidone (6), irigenin (8), stigmasterol-3-O-β-D-glucopyranoside (9), irilone 4-O--D-glucopyranoside (10) and iridin (11). Their structures were established by UV, IR, 1D (1H and 13C) and 2D