new developments in osteoarthritis. prevention of injury-related knee osteoarthritis opportunities for the primary and secondary prevention of knee osteoarthritis骨关节炎的新发展。.pdfVIP

Ratzlaf and Liang Arthritis Research Therapy 2010, 12:215 /content/12/4/215 R E V I E W Prevention of injury-related knee osteoarthritis: opportunities for the primary and secondary prevention of knee osteoarthritis 1,2 3,4 Charles R Ratzlaf * and Matthew H Liang review is to detail the biological and clinical data that Abstract make this subset of OA an attractive public health target. Where risk factors have been identii ed in knee and hip osteoarthritis (OA), with few exceptions, no prevention Joint injury increases the risk of knee osteoarthritis strategies have proven benei cial. The major risk factors h e incidence and prevalence of severe knee injuries for knee OA are advanced age, injury and obesity. requiring medical attention are not well documented. However, there is limited or no evidence that they h e diff erential diagnosis of knee injuries includes are modii able or to what degree modifying them is contusion, subchondral or chondral injury with and ef ective in preventing development of knee OA or without meniscal tear and with and without ligamentous in preventing symptoms and progressive disease in injury or complete tear. In the best studied sports persons with early OA. The notable exception is the injuries, even injury not precipitating a medical visit growing epidemic of (sports) injury related knee OA. appears to be a risk factor for knee OA; the rate is high T