new tricks for an old-favorite model新把戏以前最喜欢的模型.pdfVIP

Meeting report New tricks for an old-favorite model Charalampos Rallis Address: University College London, Department of Genetics, Evolution Environment and UCL Cancer Institute, Darwin Building, Gower Street, London WC1E 6BT, UK. Email: c.rallis@ucl.ac.uk Drosophila involves transcriptional regulation of ribo­ Abstract somal and metabolic genes. Suppression of the Drosophila A report of the 24th International Conference on Yeast Genetics TOR pathway results in prolonged pre­adult development and Molecular Biology, Manchester, UK, 19-24 July 2009. and reduced larval and adult body sizes. TOR is linked to aging from yeast to mammals and deregulation of the The international yeast meetings are highly interactive pathway causes disease in humans (such as cancer, cardiac conferences attracting scientists from diverse disciplines of hypertrophy and inflammatory diseases). Mike Hall fungal research. The 24th yeast meeting held in the (Biozentrum, University of Basel, Switzerland) discussed University of Manchester presented recent advances rang­ recent findings of his group regarding the cross­talk ing from basic cell biology to the use of yeast for industrial between TOR with the protein kinase A (PKA) signaling purposes and translational research. Here, I summarize a pathway, which controls many similar processes. They few highlights