nos2 polymorphisms associated with the susceptibility to pulmonary arterial hypertension with systemic sclerosis contribution to the transcriptional activitynos2多态性与易感性相关肺动脉高血压与系统性硬化症贡献转录活动.pdfVIP

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nos2 polymorphisms associated with the susceptibility to pulmonary arterial hypertension with systemic sclerosis contribution to the transcriptional activitynos2多态性与易感性相关肺动脉高血压与系统性硬化症贡献转录活动.pdf

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nos2 polymorphisms associated with the susceptibility to pulmonary arterial hypertension with systemic sclerosis contribution to the transcriptional activitynos2多态性与易感性相关肺动脉高血压与系统性硬化症贡献转录活动

Available online /content/8/4/R104 Vol 8 No 4 Open Access Research article NOS2 polymorphisms associated with the susceptibility to pulmonary arterial hypertension with systemic sclerosis: contribution to the transcriptional activity 1 1 1 1 1 Yasushi Kawaguchi , Akiko Tochimoto , Masako Hara , Manabu Kawamoto , Tomoko Sugiura , 1 2 2 3 1 Yasuhiro Katsumata , Jun Okada , Hirobumi Kondo , Mitsuo Okubo and Naoyuki Kamatani 1Institute of Rheumatology, Tokyo Womens Medical University, Tokyo, Japan 2Department of Internal Medicine, Kitasato University School of Medicine, Sagamihara, Japan 3Transfusion Medicine and Cell Therapy, Saitama Medical School, Kawagoe, Japan Corresponding author: Yasushi Kawaguchi, y-kawa@ior.twmu.ac.jp Received: 22 Feb 2006 Revisions requested: 27 Apr 2006 Revisions received: 14 May 2006 Accepted: 2 Jun 2006 Published: 3 Jul 2006 Arthritis Research Therapy 2006, 8:R104 (doi:10.1186/ar1984) This article is online at: /content/8/4/R104 © 2006 Kawaguchi et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Systemic sclerosis (SSc) is a connective tissue disease kilobases. There were significant differences in single characterized by tissue fibrosis. One of several complic