原创力文档offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment抵消remifentanil药效学的影响和安全的重症监护室患者不同程度的肾功能损害.pdfVIP
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offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment抵消remifentanil药效学的影响和安全的重症监护室患者不同程度的肾功能损害
Available online /content/8/1/R21
Research Open Access
Offset of pharmacodynamic effects and safety of remifentanil in
intensive care unit patients with various degrees of renal
impairment
1 2 3 4 5 6
Des Breen , Alexander Wilmer , Andrew Bodenham , Vagn Bach , Jan Bonde , Paul Kessler ,
Sven Albrecht7 and Soraya Shaikh8
1Consultant in Anaesthesia and Intensive Care, ICU, Royal Hallamshire Hospital, Sheffield, UK
2Associate Professor of Medicine, MICU, UZ Gasthuisberg, Leuven, Belgium
3Consultant in Anaesthesia and Intensive Care, ICU, Leeds General Infirmary, Leeds, UK
4Director of Intensive Care, Hillerod Syngehus, Hillerod, Denmark
5Consultant in Intensive Care, Amtssygehuset i Herlev, Herlev, Denmark
6Assistant Professor of Anaesthesiology, ICU, J-W Goethe Universitat, Klinik fuer Anaesthesiologie, Frankfurt, Germany
7Professor and Vice Chairman, ICU, Universitat Erlangen-Nurnberg, Klinik fur Anaesthesiologie, Erlangen, Germany
8Global Study Manager, GlaxoSmithKline RD, Greenford, UK
Correspondence: Des Breen, des.breen@
Received: 2 October 2003 Critical Care 2004, 8:R21-R30 (DOI 10.1186/cc2399)
Accepted: 16 October 2003 This article is online at /content/8/1/R21
© 2004 Breen et al., licensee BioMed Central Ltd
Published: 21 November 2003 (Print ISSN 1364-8535; Online ISSN 1466-609X). This is an Open
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