predicting late anemia in critical illness预测晚期贫血严重疾病.pdf

Available online /content/10/1/R39 Vol 10 No 1 Open Access Research Predicting late anemia in critical illness Eric B Milbrandt, Gilles Clermont, Javier Martinez, Alex Kersten, Malik T Rahim and Derek C Angus The CRISMA Laboratory (Clinical Research, Investigation, and Systems Modeling of Acute Illness), Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 3550 Terrace Street, Pittsburgh, PA 15261, USA Corresponding author: Gilles Clermont, clermontg@ Received: 6 Dec 2005 Revisions requested: 5 Jan 2006 Revisions received: 3 Feb 2006 Accepted: 9 Feb 2006 Published: 28 Feb 2006 Critical Care 2006, 10:R39 (doi:10.1186/cc4847) This article is online at: /content/10/1/R39 © 2006 Milbrandt et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Identifying critically ill patients most likely to benefit or developed late anemia. We then constructed a point system from pre-emptive therapies will become increasingly important if to quantify, within six hours of ICU admission, the likelihood of therapies are to be used safely and cost-effectively. We sought developing late anemia. to determine whether a predictive model could be constructed that would serve as a useful decision support tool for the pre- Results Models showed good discrimination with receiver emptive management of intensive care unit (ICU)-related operating characteristic curve are