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probiotics in treatment of allergic rhinitis益生菌治疗过敏性鼻炎
REVIEWS
Probiotics in Treatment of Allergic Rhinitis
Rashmi Ranjan Das, MD,1 Meenu Singh, MD, FIAP, FCCP,2 and Nusrat Shafiq, MD, DM3
views shows that probiotics are beneficial for treating infec-
Abstract: Many randomized controlled trials (RCTs) have been
tious diarrhea, preventing antibiotic-associated diarrhea, and
done on role of probiotics as a treatment modality in allergic rhinitis. 3–5
treating vaginal infections in pregnancy. They have been
We conducted a review on the same. A systematic search of
formally investigated in a number of clinical trials for the
published literature was done. RCTs comparing effect of probiotics
treatment of seasonal and perennial AR with variable results.
with placebo were included. A predefined set of outcome measures
The aim of the present paper is to find whether probiotics are
were assessed. Continuous data were expressed as pooled standard-
effective in treatment of AR or not.
ized mean difference (SMD) with 95% confidence interval (CI).
Dichotomous data were expressed as odds ratio with 95% CI. P
METHOD
value 0.05 was considered significant. RevMan version 5 was used
for
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