原创力文档protective effect of resin adsorption on septic plasma-induced tubular injury在脓毒性保护作用的树脂吸附plasma-induced管损伤.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
protective effect of resin adsorption on septic plasma-induced tubular injury在脓毒性保护作用的树脂吸附plasma-induced管损伤
Cantaluppi et al. Critical Care 2010, 14:R4
/content/14/1/R4
RESEARCH Open Access
Protective effect of resin adsorption on septic
plasma-induced tubular injury
1,2 3 1 1 1 1,2
Vincenzo Cantaluppi , Viktoria Weber , Carola Lauritano , Federico Figliolini , Silvia Beltramo , Luigi Biancone ,
4 4 4 2 5 1,2,6*
Massimo De Cal , Dinna Cruz , Claudio Ronco , Giuseppe Paolo Segoloni , Ciro Tetta , Giovanni Camussi
Abstract
Introduction: A pro-apoptotic effect of circulating mediators on renal tubular epithelial cells has been involved in
the pathogenesis of sepsis-associated acute kidney injury (AKI). Adsorption techniques have been showed to
efficiently remove inflammatory cytokines from plasma. The aim of this study was to evaluate the efficiency of the
hydrophobic resin Amberchrom CG161 M to adsorb from septic plasma soluble mediators involved in tubular
injury.
Methods: We enrolled in the study 10 critically ill patients with sepsis-associated AKI and we evaluated the effects
of their plasma on granulocyte adhesion, apoptosis and functional alterations of cultured human kidney tubular
epithelial cells. We established an in vitro model of plasma adsorption and we studied the protective effect of
unselective removal of soluble mediators by the Amberchrom CG161 M resin on septic plasma-induced tubular cell
injury.
Results: Plasma from septic patients induced granulocyte adhesion, apoptosis and altered polarity in tubular cells.
Plasma adsorption significantly decreased these effects and abated the concentrations of several soluble mediators
您可能关注的文档
- primary pleural angiosarcoma as a mimicker of mesothelioma a case report主要胸膜间皮瘤案例报告的血管肉瘤是模仿别人的人.pdf
- primary, secondary metabolites, h2o2, malondialdehyde and photosynthetic responses of orthosiphon stimaneus benth. to different irradiance levels一级,二级代谢物,过氧化氢,丙二醛和光合反应的orthosiphon stimaneus benth。.pdf
- primary pulmonary malignant melanoma a clinicopathologic study of two cases原发性肺恶性黑色素瘤的临床病理的研究两种情况.pdf
- primary prevention of allergic diseases current concepts and mechanisms过敏性疾病的初级预防当前概念和机制.pdf
- primary submucosal nodular plasmacytoma of thestomach a poorly recognized variant of gastriclymphoma胃里的主要黏膜下结节性浆细胞瘤gastriclymphoma公认的变异体.pdf
- primed for discovery atomic-resolution cryo-em structure of a reovirus entry intermediate准备发现原子水平的低温电子显微镜结构中间呼肠孤病毒条目.pdf
- principles of cartilage tissue engineering in tmj reconstruction软骨组织工程原理在颞下颌关节重建.pdf
- principal component and factor analytic models in international sire evaluation主成分和因子分析模型在国际陛下评估.pdf
- primary mucinous cystadenoma of the spermatic cord within the inguinal canal精索的主要粘液性囊腺瘤在腹股沟管.pdf
- primate-specific evolution of an ldlr enhancerprimate-specific进化ldlr的增强剂.pdf
- protein c a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated)蛋白质c潜在生物标志物在严重脓毒症和可能的工具来监控治疗drotrecogin阿尔法(激活).pdf
- protein biomarkers in cystic fibrosis research where next蛋白质生物标记物在囊性纤维化的研究.pdf
- protein c concentrations in severe sepsis an early directional change in plasma levels predicts outcome蛋白c浓度严重脓毒症早期定向改变等离子体水平预测的结果.pdf
- protein function annotation by homology-based inference同源蛋白质功能注释的推理.pdf
- protein biosensors based on polymer nanowires, carbon nanotubes and zinc oxide nanorods蛋白质基于聚合物纳米线生物传感器、碳纳米管和氧化锌纳米棒.pdf
- protein disorder in plants a view from the chloroplast从叶绿体蛋白质障碍在植物一个视图.pdf
- protein expression of g-protein inwardly rectifying potassium channels (girk) in breast cancer cells蛋白的蛋白质表达内心整流钾通道(girk)在乳腺癌细胞.pdf
- protein quadratic indices of the “macromolecular pseudograph’s α-carbon atom adjacency matrix”. 1. prediction of arc repressor alanine-mutant’s stability蛋白质的二次指数u201c大分子伪书α-carbon原子邻接矩阵u201d。.pdf
- protein domain analysis of c. botulinum type a neurotoxin and its relationship with other botulinum serotypes肉毒蛋白质域分析c型肉毒神经毒素及其关系与其他血清型.pdf
- protein kinases as drug development targets for heart disease therapy蛋白激酶作为心脏疾病治疗药物开发的目标.pdf
文档评论（0）