psychosocial functioning in patients with treatment-resistant depression after group cognitive behavioral therapy在难治性抑郁症患者的心理社会功能团体认知行为疗法.pdfVIP

Matsunaga et al. BMC Psychiatry 2010, 10:22 /1471-244X/10/22 RESEARCH ARTICLE Open Access Psychosocial functioning in patients with treatment-resistant depression after group cognitive behavioral therapy Miki Matsunaga1,2†, Yasumasa Okamoto1†, Shin-ichi Suzuki3†, Akiko Kinoshita1†, Shinpei Yoshimura1†, Atsuo Yoshino1†, Yoshihiko Kunisato1†, Shigeto Yamawaki1* Abstract Background: Although patients with Treatment Resistant Depression (TRD) often have impaired social functioning, few studies have investigated the effectiveness of psychosocial treatment for these patients. We examined whether adding group cognitive behavioral therapy (group-CBT) to medication would improve both the depressive symptoms and the social functioning of patient with mild TRD, and whether any improvements would be maintained over one year. Methods: Forty-three patients with TRD were treated with 12 weekly sessions of group-CBT. Patients were assessed with the Global Assessment of Functioning scale (GAF), the 36-item Short-Form Health Survey (SF-36), the Hamilton Rating Scale for Depression (HRSD), the Dysfunctional Attitudes Scale (DAS), and the Automatic Thought Questionnaire-Revised (ATQ-R) at baseline, at the termination of treatment, and at the 12-month follow-up. Results: Thirty-eight patients completed treatment; five dropped out. For the patients who completed treatment, post-treatment scores on the GAF and SF-36 were significantly higher than baseline scores. Scores on the HRSD, DAS, and ATQ-R were significantly lower after the treatment. Thus patients improved on all measurements of psychosocial functioning and mood symptoms. Twenty patients participated in the 12-month follow-up. Their improvements for psychosocial functioning, depressive symptoms, and dysfunctional cognitions were sustained at 12 months following the completion