recombinant activated protein c treatment improves tissue perfusion and oxygenation in septic patients measured by near-infrared spectroscopy重组蛋白c激活发生在败血症患者治疗可以改善组织灌注和氧合通过近红外光谱测量.pdfVIP

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recombinant activated protein c treatment improves tissue perfusion and oxygenation in septic patients measured by near-infrared spectroscopy重组蛋白c激活发生在败血症患者治疗可以改善组织灌注和氧合通过近红外光谱测量.pdf

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recombinant activated protein c treatment improves tissue perfusion and oxygenation in septic patients measured by near-infrared spectroscopy重组蛋白c激活发生在败血症患者治疗可以改善组织灌注和氧合通过近红外光谱测量

Available online /content/13/S5/S12 Research Recombinant activated protein C treatment improves tissue perfusion and oxygenation in septic patients measured by near-infrared spectroscopy 1 1 1 1 1 Abele Donati , Michela Romanelli , Laura Botticelli , Agnese Valentini , Vincenzo Gabbanelli , Simonetta Nataloni1 1 1 2 2 , Tiziana Principi , Paolo Pelaia , Rick Bezemer and Can Ince 1Department of Neuroscience, Intensive Care Unit, Marche Polytechnical University, Via Tronto 10/A, 60020 Torrette di Ancona, Italy 2Department of Intensive Care, Erasmus MC University Hospital Rotterdam, 3000 Rotterdam, The Netherlands Corresponding author: Abele Donati, a.donati@univpm.it Published: 30 November 2009 Critical Care 2009, 13(Suppl 5):S12 (doi:10.1186/cc8010) This article is online at /content/13/S5/S12 © 2009 BioMed Central Ltd Abstract and at T1b and T2 (–16.5 ± 11.8 vs. –8.1 ± 2.4%/minute) was Introduction: The purpose was to test the hypothesis that muscle significantly steeper than in the control group. StO2 upslope increased and was higher than in the control group at T1c, T1d perfusion, oxygenation, and microvascular reactivity would improve and T2 (101.1 ± 62.1 vs. 54.5 ± 23.8%/minute)