repeatability of corticospinal and spinal measures during lengthening and shortening contractions in the human tibialis anterior muscle重复性的皮质脊髓和脊髓措施在延长和缩短人的胫骨前肌收缩.pdfVIP

Repeatability of Corticospinal and Spinal Measures during Lengthening and Shortening Contractions in the Human Tibialis Anterior Muscle 1 1 ´ 2 1 1 Jamie Tallent , Stuart Goodall , Tibor Hortobagyi , Alan St Clair Gibson , Duncan N. French , Glyn Howatson1,3* 1 School of Life Sciences, Northumbria University, Newcastle-upon-Tyne, United Kingdom, 2 University Medical Center of Groningen, University of Groningen, Groningen, The Netherlands, 3 Centre for Aquatic Research, University of Johannesburg, Gauteng, South Africa Abstract Elements of the human central nervous system (CNS) constantly oscillate. In addition, there are also methodological factors and changes in muscle mechanics during dynamic muscle contractions that threaten the stability and consistency of transcranial magnetic stimulation (TMS) and perpherial nerve stimulation (PNS) measures.Purpose: To determine the repeatability of TMS and PNS measures during lengthening and shortening muscle actions in the intact human tibialis anterior. Methods: On three consecutive days, 20 males performed lengthening and shortening muscle actions at 15, 25, 50 and 80% of maximal voluntary contraction (MVC). The amplitude of the Motor Evoked Potentials (MEPs) produced by TMS was measured at rest and during muscle contraction at 90u of ankle joint position. MEPs were normalised to Mmax determined with PNS. The corticospinal silent period was recorded at 80% MVC. Hoffman reflex (H-reflex) at 10% isometric and 25% shortening and lengthening MVCs, and V-waves during MVCs were also evoked on each of the three days. Results: With the exception of MEPs evoked at 80% shortening MVC, all TMS-derived measures showed good