原创力文档resting heart rate as a predictor of metabolic dysfunctions in obese children and adolescents静息心率作为预测代谢障碍在肥胖儿童和青少年.pdfVIP
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resting heart rate as a predictor of metabolic dysfunctions in obese children and adolescents静息心率作为预测代谢障碍在肥胖儿童和青少年
Freitas Júnior et al. BMC Pediatrics 2012, 12:5
/1471-2431/12/5
RESEARCH ARTICLE Open Access
Resting heart rate as a predictor of metabolic
dysfunctions in obese children and adolescents
1 2 2 1 1
Ismael F Freitas Júnior , Paula A Monteiro , Loreana S Silveira , Suziane U Cayres , Bárbara M Antunes ,
2 3 4 1*
Karolynne N Bastos , Jamile S Codogno , João Paulo J Sabino and Rômulo A Fernandes
Abstract
Background: Recent studies have identified that a higher resting heart rate (RHR) is associated with elevated
blood pressure, independent of body fatness, age and ethnicity. However, it is still unclear whether RHR can also
be applied as a screening for other risk factors, such as hyperglycemia and dyslipidemia. Thus, the purpose of the
presented study was to analyze the association between RHR, lipid profile and fasting glucose in obese children
and adolescents.
Methods: The sample was composed of 180 obese children and adolescents, aged between 7-16 years. Whole-
body and segmental body composition were estimated by Dual-energy X-ray absorptiometry. Resting heart rate
(RHR) was measured by heart rate monitors. The fasting blood samples were analyzed for serum triglycerides, total
cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and
glucose, using the colorimetric method.
Results: Fasting glucose, TC, triglycerides, HDL-C, LDL-C and RHR were similar in both genders. The group of obese
subjects with a higher RHR presented, at a lower age, higher triglycerides and TC. There was a significant
relationship between RHR, tr
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