risk of hematological malignancies associated with magnetic fields exposure from power lines a case-control study in two municipalities of northern italy血液恶性肿瘤与磁场相关的风险敞口从电线意大利北部的病例对照研究在两个直辖市.pdfVIP
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risk of hematological malignancies associated with magnetic fields exposure from power lines a case-control study in two municipalities of northern italy血液恶性肿瘤与磁场相关的风险敞口从电线意大利北部的病例对照研究在两个直辖市
Malagoli et al. Environmental Health 2010, 9:16
/content/9/1/16
RESEARCH Open Access
Risk of hematological malignancies associated
with magnetic fields exposure from power lines:
a case-control study in two municipalities of
northern Italy
1 2 2 3 4 4 5
Carlotta Malagoli , Sara Fabbi , Sergio Teggi , Mariagiulia Calzari , Maurizio Poli , Elena Ballotti , Barbara Notari ,
5 6 6 1*
Maurizio Bruni , Giovanni Palazzi , Paolo Paolucci , Marco Vinceti
Abstract
Background: Some epidemiologic studies have suggested an association between electromagnetic field exposure
induced by high voltage power lines and childhood leukemia, but null results have also been yielded and the
possibility of bias due to unmeasured confounders has been suggested.
Methods: We studied this relation in the Modena and Reggio Emilia municipalities of northern Italy, identifying the
corridors along high voltage power lines with calculated magnetic field intensity in the 0.1-0.2, 0.2-0.4, and ≥ 0.4
microTesla ranges. We identified 64 cases of newly-diagnosed hematological malignancies in children aged 14
within these municipalities from 1986 to 2007, and we sampled four matched controls for each case, collecting
information on historical residence and parental socioeconomic status of these subjects.
Results: Relative risk of leukemia associated with antecedent residence in the area with exposure ≥ 0.1 microTesla
was 3.2 (6.7 adjusting for socioeconomic status), but this estimate was statistically very unstable, its 95% confidence
interval being 0.4-23.4, and no indication of a dose-response relation emerged. Relative risk for acute lymphoblastic
leukemia
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