scutellaria baicalensis alleviates cantharidin-induced rat hemorrhagic cystitis through inhibition of cyclooxygenase-2 overexpression黄芩减轻cantharidin-induced通过抑制大鼠出血性膀胱炎cyclooxygenase-2超表达.pdfVIP

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scutellaria baicalensis alleviates cantharidin-induced rat hemorrhagic cystitis through inhibition of cyclooxygenase-2 overexpression黄芩减轻cantharidin-induced通过抑制大鼠出血性膀胱炎cyclooxygenase-2超表达.pdf

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scutellaria baicalensis alleviates cantharidin-induced rat hemorrhagic cystitis through inhibition of cyclooxygenase-2 overexpression黄芩减轻cantharidin-induced通过抑制大鼠出血性膀胱炎cyclooxygenase-2超表达

Molecules 2012, 17, 6277-6289; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Scutellaria baicalensis Alleviates Cantharidin-Induced Rat Hemorrhagic Cystitis through Inhibition of Cyclooxygenase-2 Overexpression Steven Kuan-Hua Huan 1,2, Kun-Teng Wang 3,4, Shauh-Der Yeh 2, Chia-Jung Lee 3, Li-Chun Lin 3, Der-Zen Liu 5 and Ching-Chiung Wang 3,* 1 Division of Urology, Department of Surgery, Chi Mei Medical Center, No.21, Taikang, Liuying Dist., Tainan City 73657, Taiwan; E-Mail: skhsteven@.tw 2 Graduate Institute of Clinical Medical Research, Taipei Medical University, 250 Wu-Hsing Street, Taipei City 11031, Taiwan; E-Mail: d8602003@.tw 3 School of Pharmacy, College of Pharmacy, Taipei Medical University, 250 Wu-Hsing Street, Taipei City 11031, Taiwan; E-Mails: b8706014@.tw (K.-T.W.); m303092003@.tw (C.-J.L.); snoopy0615@ (L.-C.L.) 4 Section of Biologics Advanced Therapeutic Product Analysis, Division of Research and Analysis, Food and Drug Administration, No.161-2, Kunyang St, Nangang District, Taipei City 11561, Taiwan 5 Graduate Institute of Biomedical Materials, Taipei Medical University, 250 Wu-Hsing Street, Taipei City 11031, Taiwan; E-Mail: tonyliu@.tw * Author to whom correspondence should be addressed; E-Mail: crystal@.tw; Tel.: +886-2-2736-1661 (ext. 6161); Fax: +886-2-2732-9368. Received: 12 April 2012; in revised form: 13 May 2012 / Accepted: 15 May 2012 / Published: 25 May 2012 Abstract: Cantharidin, an active component in mylabris, is used in traditional Chinese