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selection and outcome of portal vein resection in pancreatic cancer选择和结果门静脉切除的胰腺癌
Cancers 2010, 2, 1990-2000; doi:10.3390/cancers2041990
OPEN ACCESS
cancers
ISSN 2072-6694
/journal/cancers
Review
Selection and Outcome of Portal Vein Resection in
Pancreatic Cancer
Akimasa Nakao
Department of Surgery II, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho,
Showa-ku, Nagoya 466-8550, Japan; E-Mail: nakaoaki@med.nagoya-u.ac.jp; Tel.: +81-52-744-2233;
Fax: +81-52-744-2255
Received: 12 October 2010; in revised form: 11 November 2010 / Accepted: 22 November 2010 /
Published: 24 November 2010
Abstract: Pancreatic cancer has the worst prognosis of all gastrointestinal neoplasms.
Five-year survival of pancreatic cancer after pancreatectomy is very low, and surgical
resection is the only option to cure this dismal disease. The standard surgical procedure is
pancreatoduodenectomy (PD) for pancreatic head cancer. The morbidity and especially the
mortality of PD have been greatly reduced. Portal vein resection in pancreatic cancer
surgery is one attempt to increase resectability and radicality, and the procedure has become
safe to perform. Clinicohistopathological studies have shown that the most important
indication for portal vein resection in patients with pancreatic cancer is the ability to obtain
cancer-free surgical margins. Otherwise, portal vein resection is contraindicated.
Keywords: pancreatic cancer; portal vein resection; isolated pancreatectomy; catheter-
bypass of the portal vein
1. History of Portal Vein Resecti
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