sleep duration, vital exhaustion and perceived stress among pregnant migraineurs and non-migraineurs睡眠时间,重要的疲惫和压力在怀孕的偏头痛患者和non-migraineurs.pdfVIP

Williams et al. BMC Pregnancy and Childbirth 2010, 10:72 /1471-2393/10/72 RESEARCH ARTICLE Open Access Sleep duration, vital exhaustion and perceived stress among pregnant migraineurs and non-migraineurs 1,2* 3 2 2 1 1 Michelle A Williams , Sheena K Aurora , Ihunnaya O Frederick , Chunfang Qiu , Bizu Gelaye , Swee May Cripe Abstract Background: Migraine has been associated with sleep disorders in men and non-pregnant women, but little is known about sleep complaints among pregnant migraineurs. Methods: A cohort of 1,334 women was interviewed during early pregnancy. At the time of interview we ascertained participants’ migraine diagnosis status and collected information about sleep duration before and during early pregnancy, daytime sleepiness, vital exhaustion and perceived stress during early pregnancy. Multivariable logistic regression procedures were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) of short/long sleep duration, excessive daytime sleepiness, vital exhaustion and elevated perceived stress associated with a history of migraine. Results: Approximately 19.4% of the cohort (n = 259) reported having a medical diagnosis of migraine prior to the study pregnancy. Compared with women without migraine, the multivariable-adjusted ORs (95% CI) among migraineurs for short sleep duration before and during early pregnancy were 1.51 (1.09-2.09), and 1.57 (1.11-2.23), respectively. The corresponding OR (95% CI) for long sleep duration before and during pregnancy were 1.33 (0.77-2.31) and 1.31 (0.94-1.83), respectively. A modest and statistically insignificant association between migraine history and excessive daytime sleepiness in early pregnancy was noted (OR = 1.46