synergistic effects of copper and butylic ester of 2,4-dichlorophenoxyacetic acid (esternon ultra) on amphibian embryos铜和butylic酯2的协同影响,现在也是酸(esternon超)两栖动物的胚胎.pdfVIP
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synergistic effects of copper and butylic ester of 2,4-dichlorophenoxyacetic acid (esternon ultra) on amphibian embryos铜和butylic酯2的协同影响,现在也是酸(esternon超)两栖动物的胚胎
Int. J. Environ. Res. Public Health 2006, 3(4) , 343-347
International Journal of
Environmental Research and Public Health
ISSN 166 1-7827
© 2006 by MDPI
Synergistic Effects of Copper and Butylic Ester of 2,4-
Dichlorophenoxyacetic Acid (Esternon Ultra) on Amphibian Embryos
Cristina Silvia Pérez-Coll 1,2,3 and Jorge Herkovits 1,2*
1Programa de Seguridad Química, Instituto de Ciencias Ambientales y Salud (ICAS), Fundación PROSAMA, Paysandú 752,
(1405) Buenos Aires, Argentina.
2Members of the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina.
3Escuela de Ciencia y Tecnología, Universidad Nacional de San Martín
*Correspondence to Dr. Jorge Herkovits. Email: herkovit@mail.retina.ar
Received: 21 December 2005/ Accepted: 10 January 2006 / Published : 31 December 2006
Abstract: Cu2+ and butylic ester of 2,4-Dichlorophenoxyacetic acid as Esternon Ultra (2,4-D) toxicity on Bufo
arenarum embryos were evaluated by means of a short-term chronic toxicity test (AMPHITOX). The NOEC values for
Cu and 2,4-D were 0.02 mg/L and 2 mg/L respectively. The toxicity profile curves for Cu and 2,4-D were reported.
The interactions of the metal and the herbicide were evaluated by combined treatments with different concentrations of
Cu and 2,4-D. Although in all cases, a synergistic effect between these chemicals was observed, the combination of
concentrations exerting
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