原创力文档synthesis of schiff and mannich bases of isatin derivatives with 4-amino-4,5-dihydro-1h-1,2,4-triazole-5-ones合成的希夫曼尼希碱与4-amino-4靛红衍生物,5-dihydro-1h-1,2,4-triazole-5-ones.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
Molecules 2008, 13, 2126-2135; DOI: 10.3390/molecule
OPEN ACCESS
molecules
ISSN 1420-3049
/molecules
Article
Synthesis of Schiff and Mannich Bases of Isatin Derivatives with
4-Amino-4,5-Dihydro-1H-1,2,4-Triazole-5-Ones
Olcay Bekircan 1, * and Hakan Bektas 2
1 Department of Chemistry, Karadeniz Technical University, 61080 Trabzon, Turkey
2 Department of Chemistry, Giresun University, 28049 Giresun, Turkey; E-mail:
hakanbektas@.tr
* Author to whom correspondence should be addressed; E-mail: obekircan@.
Received: 15 August 2008; in revised form: 28 August 2008 / Accepted: 1 September 2008 / Published:
10 September 2008
Abstract: Ethyl imidate hydrochlorides 1 were prepared by passing HCl gas through
solutions of substituted benzyl cyanides and absolute ethanol. Ethoxycarbonylhydrazones
2 were synthesized from the reaction of compounds 1 with ethyl carbazate. Treatment of 2
with hydrazine hydrate leads to the formation of substituted 4-amino-4,5-dihydro-1H-
1,2,4-triazole-5-ones 3. Isatin and 5-chloroisatin were added to 3 to form Schiff bases 4
and N-Mannich bases 5 of these compounds were synthesized by reacting with
formaldehyde and piperidine. Their chemical structures were confirmed by means of IR,
1H- and 13C-NMR data and by elemental analysis.
Keywords: Ethyl imidate hydrochloride; ethoxycarbonyl hydrazones; 4-amino-1,2,4-
triazole-5-one; isatin; Schiff bases; Mannich bases.
Introduction
Schiff bases are
您可能关注的文档
- swedish population substructure revealed by genome-wide single nucleotide polymorphism data瑞典人口子结构揭示了全基因组单核苷酸多态性数据.pdf
- sweet success, bitter defeat a taste phenotype predicts social status in selectively bred rats甜成功,苦失败体验表型预测社会地位在选择性繁殖老鼠.pdf
- svr with hybrid chaotic immune algorithm for seasonal load demand forecastingsvr与混合混沌免疫算法对季节性负荷需求预测.pdf
- sweepoviruses cause disease in sweet potato and related ipomoea spp. fulfilling koch's postulates for a divergent group in the genus begomovirussweepoviruses引起疾病的红薯和相关的番薯spp。实现科赫法则属begomovirus发散集团.pdf
- swedish snus and the gothiatek？ standard瑞典鼻烟和gothiatek 标准.pdf
- swelling-activated anion channels are essential for volume regulation of mouse thymocytesswelling-activated阴离子通道音量调节的小鼠胸腺细胞至关重要.pdf
- swelling-activated ca2+ channels trigger ca2+ signals in merkel cellsswelling-activated ca2 +渠道引发在默克尔细胞钙离子信号.pdf
- swine influenza viruses isolated in 1983, 2002 and 2009 in sweden exemplify different lineages猪流感病毒隔离在1983年、2002年和2009年在瑞典体现不同的血统.pdf
- switched flip-flop based preprocessing circuit for isfets基于切换触发器为isfets预处理电路.pdf
- swinholide j, a potent cytotoxin from the marine sponge theonella swinhoeiswinholide j,一个强有力的细胞毒素的海洋海绵theonella swinhoei.pdf
- synthesis of seco-chlorinated derivatives of phenanthroindolizidine precursors via friedel-crafts reactionphenanthroindolizidine seco-chlorinated衍生品的合成前体通过傅克反应.pdf
- synthesis of n-substituted 5-iodouracils as antimicrobial and anticancer agents合成n - 5-iodouracils抗菌、抗癌剂.pdf
- synthesis of some new fluorinated hexahydroquinoline and acridinedione derivatives in trifluoroethanol合成一些新的氟hexahydroquinoline trifluoroethanol acridinedione衍生品.pdf
- synthesis of some new bis-schiff bases of isatin and 5-fluoroisatin in a water suspension medium合成一些新的bis-schiff基地靛红和5-fluoroisatin水悬浮介质.pdf
- synthesis of some new mono- and bis-polycyclic aromatic spiro and bis-nonspiro-β-lactams合成一些新的mono -和bis-polycyclic芳斯皮罗和bis-nonspiro-β-lactams.pdf
- synthesis of some new pyridine-2,6-carboxamide-derived schiff bases as potential antimicrobial agents合成一些新的pyridine-2,6-carboxamide-derived希夫碱作为潜在的抗菌药物.pdf
- synthesis of some phenylpropanoid monoglycerides via the mitsunobu protocol一些phenylpropanoid合成单甘酯通过mitsunobu协议.pdf
- synthesis of some phenylpropanoid glycosides (ppgs) and their acetylcholinesterasexanthine oxidase inhibitory activities合成一些phenylpropanoid苷(ppg)及其acetylcholinesterasexanthine氧化酶抑制活动.pdf
- synthesis of some oxadiazole derivatives as new anticandidal agents合成一些oxadiazole衍生品新anticandidal代理.pdf
- synthesis of some new 4,5-substituted-4h-1,2,4-triazole-3-thiol derivatives合成一些新的4,5-substituted-4h-1 2 4-triazole-3-thiol衍生品.pdf
文档评论（0）