the eyes have it regulatory and structural changes both underlie cichlid visual pigment diversity眼睛有监管和结构性变化都是丽鱼科鱼的视觉色素的多样性的基础.pdfVIP

The Eyes Have It: Regulatory and Structural Changes Both Underlie Cichlid Visual Pigment Diversity 1. 1. 2 3 Christopher M. Hofmann *, Kelly E. O’Quin , N. Justin Marshall , Thomas W. Cronin , Ole Seehausen4,5, Karen L. Carleton1 1 Department of Biology, University of Maryland, College Park, Maryland, United States of America, 2 Sensory Neurobiology Group, School of Biomedical Sciences University of Queensland, St. Lucia, Queensland, Australia, 3 Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, Maryland, United States of America, 4 Aquatic Ecology and Evolution, Institute of Ecology and Evolution, University of Bern, Bern, Switzerland, 5 Eawag, Swiss Federal Institute for Aquatic Science and Technology, Centre of Ecology, Evolution and Biogeochemistry, Kastanienbaum, Switzerland Abstract A major goal of evolutionary biology is to unravel the molecular genetic mechanisms that underlie functional diversification and adaptation. We investigated how changes in gene regulation and coding sequence contribute to sensory diversification in two replicate radiations of cichlid fishes. In the clear waters of Lake Malawi, differential opsin expression generates diverse visual systems, with sensitivities extending from the ultraviolet to the red regions of the spectrum. These sensitivities fall into three distinct clusters and are correlated with foraging habits. In the turbid waters of Lake Victoria, visual sensitivity is constrained to longer wavelengths, and opsin expression is correlated with ambient light. In addition to regulatory changes, we found that the opsins coding for the shortest- and longest-wavelength visual pigments have elevated numbers of potentially functional sub