unifying candidate gene and gwas approaches in asthma统一的候选基因在哮喘和gwas的方法.pdfVIP

Unifying Candidate Gene and GWAS Approaches in Asthma 1 2 3 4 5 6 Sven Michel , Liming Liang , Martin Depner , Norman Klopp , Andreas Ruether , Ashish Kumar , 1 7 3 8 9 Michaela Schedel , Christian Vogelberg , Erika von Mutius , Andrea von Berg , Albrecht Bufe , Ernst Rietschel10, Andrea Heinzmann11, Otto Laub12, Burkhard Simma13, Thomas Frischer14, Jon Genuneit15, 16,17 5 16 4 1 Ivo G. Gut , Stefan Schreiber , Mark Lathrop , Thomas Illig , Michael Kabesch * 1 Center for Pediatrics, Clinic for Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany, 2 Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America, 3 University Children’s Hospital, Ludwig Maximilian’s University, Munich, Germany, 4 Institute of Epidemiology, Helmholtz Centre Munich, Neuherberg, Germany, 5 Institute of Clinical Molecular Biology, University Hospital Schleswig- Holstein, Campus Kiel, Kiel, Germany, 6 Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, 7 University Children’s Hospital, Technical University Dresden, Dresden, Germany, 8 Research Institute for the Prevention of Allergic Diseases, Children’s Department, Marien-Hospital, Wesel, Germany, 9 Department of Experimental Pneumology, Ruhr-University, Bochum, Germany, 10 University Children’s Hospital, University of Cologne, Cologne, Germany, 11 University Children’s Hospita