原创力文档the p53 tumor suppressor is stabilized by inhibitor of growth 1 (ing1) by blocking polyubiquitinationp53肿瘤抑制是稳定增长的抑制剂1(ing1)通过阻断polyubiquitination.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
the p53 tumor suppressor is stabilized by inhibitor of growth 1 (ing1) by blocking polyubiquitinationp53肿瘤抑制是稳定增长的抑制剂1(ing1)通过阻断polyubiquitination
The p53 Tumor Suppressor Is Stabilized by Inhibitor of
Growth 1 (ING1) by Blocking Polyubiquitination
1. 1. 1 1 2
Subhash Thalappilly , Xiaolan Feng , Svitlana Pastyryeva , Keiko Suzuki , Daniel Muruve , Daniel
3 4 5 6 1 7
Larocque , Stephane Richard , Matthias Truss , Andreas von Deimling , Karl Riabowol , Gesche Tallen *
1 Departments of Biochemistry and Molecular Biology and Oncology, University of Calgary, Calgary, Alberta, Canada, 2 Department of Medicine, University of Calgary,
Calgary, Alberta, Canada, 3 Preclinical Research Team on Neurodegenerative Diseases, Chronic Disorders DAP, GlaxoSmithKline Biologicals North America, Laval, Quebec,
Canada, 4 Department of Medicine and Oncology, Lady Davis Institute, McGill University, Montreal, Quebec, Canada, 5 Laboratory for Molecular Biology, Department of
´ ¨
Pediatrics, Charite - Universitatsmedizin Berlin, Berlin, Germany, 6 Department of Neuropathology, Institute of Pathology, Ruprecht-Karls University Heidelberg and Clinical
´ ¨
Cooperation Unit Neuropathology, Heidelberg, Germany, 7 Department of Pediatric Oncology/Haematology, Charite - Universitatsmedizin Berlin, Berlin, Germany
Abstract
The INhibitor of Growth tumor suppressors (ING1-ING5) affect aging, apoptosis, DNA repair and tumorigenesis. Plant
homeodomains (PHD) of ING proteins bind histones in a methylation-sensitive manner to regulate chromatin structure.
ING1 and ING2 contain a polybasic
您可能关注的文档
- an unbiased scientific record should be everyone's agenda一个公正的科学记录应每个人的议程.pdf
- [5-(1,3-diphenyl-1h-pyrazol-4-yl)-3-phenyl-4,5-dihydropyrazol-1-yl](pyridin-4-yl)methanone英文论文.pdf
- a standard addition method to assay the concentration of biologically interesting polyphenols in grape berries by reversed-phase hplc一个标准添加法测定的浓度生物有趣的多酚类物质在葡萄浆果反相高效液相色谱法.pdf
- antioxidant, total phenolic content and cytotoxicity evaluation of selected malaysian plants抗氧化剂,总酚含量和细胞毒性的评价选择马来西亚植物.pdf
- 3-amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3h-chromeno [2,3-d ]pyrimidine an effecient key precursor for novel synthesis of some interesting triazines and triazepines as potential anti-tumor agents英文论文.pdf
- amélioration de la productivité des brebis berrichonnes du cher par croisement. iii. – performances de reproduction des trois premières genérations de brebis croisées entre les races berrichonne du cher et romanov英文论文.pdf
- carnivory in the teasel dipsacus fullonum — the effect of experimental feeding on growth and seed set在川续断carnivory dipsacus fullonumu2014u2014实验喂养对增长的影响和种子.pdf
- common variants in crp and lepr influence high sensitivity c-reactive protein levels in north indians常见的变体c反应蛋白和lepr影响灵敏度高c反应蛋白水平在北印度人.pdf
- arntl (bmal1) and npas2 gene variants contribute to fertility and seasonalityarntl(bmal1)和npas2基因变异导致生育和季节性.pdf
- cost-effectiveness of blood agar for isolation of mycobacteria成本效益的血琼脂分枝杆菌的隔离.pdf
- the parasexual cycle in candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains白色念珠菌的准性的周期提供了另一种途径减数分裂重组菌株的形成.pdf
- the park 51ground zero controversy and sacred sites as contested space世贸大厦遗址公园51争议和圣地有争议的空间.pdf
- the ultrastructure of book lung development in the bark scorpion centruroides gracilis (scorpiones buthidae)皮书肺超微结构的发展蝎子centruroides股薄肌(蝎子buthidae).pdf
- the pamino-project evaluating a primary care-based educational program to improve the quality of life of palliative patientspamino-project评估主要care-based教育计划来提高临终患者的生活质量.pdf
- the parametric, psychological, neuropsychological, and neuroanatomical properties of self and world evaluation参数、心理、神经心理学和神经解剖学的自我和世界的属性评估.pdf
- the partial regression coefficients in pedigree evaluation血统的偏回归系数的评估.pdf
- the parenting attitudes and the stress of mothers predict the asthmatic severity of their children a prospective study母亲的教养态度和压力预测孩子的哮喘严重程度的前瞻性研究.pdf
- the past and future of tuberculosis research结核病研究的过去和未来.pdf
- over-expression of glutamine synthase in focal nodular hyperplasia (part 1) early stages in the formation support the hypothesis of a focal hyper-arterialisation with venous (portal and hepatic) and biliary damage英文论文.pdf
- the pathogenesis of rift valley fever裂谷热的发病机理.pdf
文档评论（0）