the physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts生理人类体内生物钟的周期长度成正比的时期人类成纤维细胞.pdfVIP
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the physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts生理人类体内生物钟的周期长度成正比的时期人类成纤维细胞
The Physiological Period Length of the Human Circadian
Clock In Vivo Is Directly Proportional to Period in Human
Fibroblasts
1. 2. 3 4 4
Lucia Pagani , Ekaterina A. Semenova , Ermanno Moriggi , Victoria L. Revell , Lisa M. Hack , Steven W.
5 4 4 1 6 7
Lockley , Josephine Arendt , Debra J. Skene , Fides Meier , Jan Izakovic , Anna Wirz-Justice , Christian
7 2 8 2 1
Cajochen , Oksana J. Sergeeva , Sergei V. Cheresiz , Konstantin V. Danilenko , Anne Eckert *, Steven A.
Brown3*
1 Neurobiology Laboratory for Brain Aging and Mental Health, Psychiatric University Clinics Basel, Basel, Switzerland, 2 Institute of Internal Medicine of the Siberian Branch
of the Russian Academy of Medical Sciences, Novosibirsk, Russia, 3 Department of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland, 4 Centre for
Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom, 5 Circadian Physiology Program, Division of Sleep Medicine,
Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, 6 Department of Dermatology, University Hospital Basel, Basel,
Switzerland, 7 Centre for Chronobiology, Psychiatric University Clinics Basel, Basel, Switzerland, 8 Institute of Cytology and Genetics of the Siberian Branch of the Russian
Academy of Sciences, Novosibirsk, Russia
Abstract
Background: Diurnal behavior in humans is governed by the period length of a circadian clock in the suprachiasmatic nuclei
of the brain hypot
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