新乡医学院机能学实验（Functional Laboratory of Xinxiang Medical University）.doc

新乡医学院机能学实验（Functional Laboratory of Xinxiang Medical University） Functional Laboratory of Xinxiang Medical University Regulation of respiratory movement and experimental acute respiratory failure Zhi Kui Yin Department of Pharmacology; Xinxiang Medical University December 3, 2006 Regulation of respiratory movement and experimental acute respiratory failure in the experiment to CHINESENUM3 = 1: The effects of nerve and other factors on respiratory movement and the discharge of phrenic nerve were observed. An animal model of oleic acid induced acute pulmonary edema. To investigate the pathogenesis of pulmonary edema with respiratory failure. The experiment principle CHINESENUM3 two = 2: Regulation of respiratory movement: Respiratory movement is a reflection of rhythmic activity of respiratory center. The central respiratory movement including the medulla and pons, by their neuronal firing, through efferent nerve (phrenic and intercostal nerve) governs breathing muscle contraction, chest expansion, to reduce the pressure in the chest, the gas through the respiratory tract into the alveolar gas exchange, to complete the respiratory movement. Rhythmic respiratory movements, although originating in the brain, can be modulated by the afferent impulses of other organ receptors, such as the respiratory organ itself and the blood circulation. Reflex regulation of respiration: (1) pulmonary stretch reflex 2) chemoreceptor respiratory reflex 3) proprioceptive reflex of respiratory muscle 4) defense reflex Pulmonary stretch reflex: reflex of inspiratory suppression or excitation caused by dilatation of the lung or atrophy of the lungs. It includes pulmonary distension reflex and pulmonary atrophy reflex. When inhaling, the lungs inflate and dilate - the receptors that stimulate the trachea into the smooth muscles of the bronchioles - - impulses through the vagus nerve to the medulla - - inhale, stop, and exhale. A reflex of the pulmonary atrophy that occurs when the lungs are a