冠状动脉介入术后应用新型血管闭合器Boomerang初步探究.docVIP

冠状动脉介入术后应用新型血管闭合器Boomerang初步探究 　 作者：王显，张健，郭实，张守彦，徐 威，李晓明，胡大一 【摘要】 目的 评价冠状动脉造影或经皮冠状动脉介入治疗（PCI）后，应用新型血管闭合器Boomerang的有效性及安全性。方法 2005年2月～2007年3月在北京军区总医院心脏中心进行冠状动脉造影或PCI的112例患者，随机应用血管闭合器Boomerang（Boomerang组，68例）和Angioseal（Angioseal组，44例）对股动脉穿刺部位进行封闭止血，观察两组止血时间、下肢制动时间，术后即刻、术后4 h、出院前24 h内出血发生率。结果 两组即刻成功率均较高（94% vs 91%，Pgt;0.05），止血时间［（1.89±1.23）min vs （2.01±1.21）min，Pgt;0.05）］，制动时间［（5.76±2.23）h vs（5.01±2.05）h，Pgt;0.05）］，两组差异均无统计学意义。术后4 h Boomerang组小出血发生率明显低于Angioseal组（7% vs 14%，Plt;0.05），两组均无大出血发生。结论 新型血管闭合器Boomerang闭合股动脉穿刺口有效、安全。 【关键词】 血管闭合器Boomerang；冠状动脉造影或PCI；经股动脉途径 Study on new vascular closer device Boomerang in patients after coronary angiography and PCI ［Abstract］ Objective The objective of this study was to examine effectivity and safety of new vascular closer device Boomerang in patients after coronary angiography（CAG） and PCI.Methods One hundred and twelve consecutive patients who were made use of Boomerang after CAG and PCI between Feb 2005～Mar 2007 at the heart centre of Beijing military district general hospital were randomly divided into Boomerang group（n=68）and angioseal group（n=44）based on femoral artery closed with Boomerang or angioseal.Hemostasis time and legs stopping time and hemorrhage incidence rate after operation immediately,4h and　24h before discharge.Results The successful rate was high in two groups（94% vs 91%,Pgt;0.05），the hemostasis time ［（1.89±1.23）min vs （2.01±1.21）min］ and legs stopping time［（5.76±2.23） h vs （5.01±2.05）h］and hemorrhage incidence rates after operation immediately and 24 h before discharge were not significant.The mini-hemorrhage incidence rate was significantly lower（7% vs 14%,Plt;0.05）after 4h in Boomerang group，no hemorrhea was seen in two groups.Conclusion New vascular closer device Boomerang is effective and safe in patients after CAG and PCI. ［Key words］ vascular closer device Boomerang,coronary angiography and PCI,femoral artery 目前在临床上较为普遍使用的血管闭合器有Angioseal、Perclose和Boomerang等，其止血原理完全不同，Boomerang血管封堵器通过前端