芬太尼加异丙酚及加咪唑安定在无痛人流中临床选择.docVIP

芬太尼加异丙酚及加咪唑安定在无痛人流中临床选择 　作者：蔡瑞音，唐松炎，许沛佳 【关键词】 芬太尼；异丙酚；咪唑安定；无痛人流 　　摘要：目的：探讨芬太尼加异丙酚与加咪唑安定在无痛人流中的临床选择。方法：将300例行人工流产术患者随机分为两组，每组150例，均于术前缓慢静脉推注芬太尼0.05～0.1mg后，观察组静脉推注异丙酚1.0～2.0mg/kg；对照组静脉推注咪唑安定0.07～0.1mg/kg。观察两组术中镇痛效果，宫颈口松弛度及人工流产综合征发生情况，比较两种方法在无痛人流术中应用的优缺点。结果：两组的镇痛效果、宫颈口松弛度及人流综合征发生情况无显著差异，观察组发生一过性呼吸抑制较对照组有显著差异。结论：两种方法均有良好的镇痛效果，但异丙酚组术中发生呼吸抑制明显高于咪唑安定组，临床上应根据患者妊娠时间、手术的难度等来选择麻醉方法。 　　关键词：芬太尼；异丙酚；咪唑安定；无痛人流 　　The Selection of with Fentanyl and Propofol in the Painless Induced Abortion 　　Abstract: Objective: To explore with fentanyl and propofol stability in the painless induced abortion. Method: 300 routine abortion patients randomly divided into two groups of trick, each 150 cases, the trick to slow intravenous push note controlled 0.05～0.1mg ago, the observing group intravenous push note propofol 1.0～2.0mg/kg; pairs intravenous push note imidazo stability 0.07～0.1mg/ kg. Observed the analgesic effect of two games, while for cervical-abortion syndrome and the occurrence, two kinds of methods to compare the advantages and disadvantages in painless induced abortion.Result: Two sets of analgesic effect, while for cervical-abortion syndrome occurred and no significant differences observed in a group of respiratory depression than in a group with significant differences. Conclusion: The analgesic effect of the two approaches is remarkable, however group games, respiratory despression occurred apparent high imidazo stability group. clinical pregnancy, the time may be based on the patients, such as surgery is the choice of narcotic means. 　　Key words:Fentanyl;Propfol;Imidazo stability 　　人工流产是终止早期妊娠的主要方法之一，手术虽短小简单，但它常给患者带来紧张、疼痛及其它不适，影响妇女的身心健康；近年来无痛人流术在妇科临床上广泛开展。本文探讨应用芬太尼加异丙酚与加咪唑安定在无痛人流术中的临床选择。 　　1资料与方法 　　1.1一般资料：将在本院行人工流产术的患者300例，随机分为两组，每组150例。孕期42～90天，年龄20～40岁，体重40～65kg，术前妇科检查，白带常规、血常规均无异常，无药物过敏史。观察组用芬太尼加异丙酚，对照组用芬太尼加咪唑安定。 　　1.2方法：术前禁食4h以上，患者取膀胱截石位，建立静脉通道，面罩吸氧2～3L/min，接监测仪，记录麻醉前后的血压、心率、血氧饱和度及呼吸情况。常规消毒后，两组术前5min经开放的静脉缓慢推注芬太尼0.05～0.1mg后，观察组静脉推注异丙酚1.0～2.0mg/kg，患者入睡后开始手术，术中必要时每次追加异丙酚0.5～1