复方玄驹胶囊对不育症亚临床精索静曲张患者精液异常的疗效.doc

复方玄驹胶囊对不育症亚临床精索静 曲张患者精液异常的疗效 陈健 王为服 岑松 刘元晓 钟江 （海南省人民医院泌尿外科 海口海南 570311） 摘要：目的：观察复方玄驹胶囊治疗亚临床型精索静脉曲张（SVC）所致不育症患者的疗效。方法：入选采用彩色多普勒及精液分析检查诊断不育症亚临床型精索静脉曲张患者62例，口服复方玄驹胶囊1.26g/次，3次/日，共3个月。结果：58例患者完成临床研究，38例为单侧SCV（左侧32例，右侧6例），20例为双侧SCV。单侧SCV患者治疗前后精子密度及精浆果糖在服药12周后与治疗前比较，有显著性改善（P＜0.05），服药6周后与治疗前比较，无显著性差异（P＞0.05）。a+b级精子百分率、精子存活率、精浆锌离子及精浆a－葡糖苷酶在服药6周、12周后均较治疗前有显著性改善（P＜0.05），服药后12周与服药后6周比较有显著性改善（P＜0.05）。双侧SCV患者治疗前后精子密度在服药12周、6周后与治疗前比较，无显著性差异。a+b级精子百分率、精子存活率、精浆果糖及a－葡糖苷酶在服药12周后与治疗前比较，有显著性改善（P＜0.05），服药6周后与治疗前比较，无显著性差异（P＞0.05）。精浆锌离子浓度在服药6周、12周后均较治疗前有显著性改善（P＜0.05），服药12周与服药6周后比较有显著性改善（P＜0.05）。结论：口服复方玄驹胶囊能改善不育症亚临床精索静脉曲张患者的精液质量。 关键词：亚临床精索静脉曲张；精液质量；不育症 中国分类号：R698 文献标识码：B The efficacy of compound xuanju capsule in the treatment of infertility caused by subclinical varicocele CHEN Jian,WANG Weifu,CEN Song,LIU Yuanxiao,ZHONG Jiang.Department of Urology,Peoples Hospital of Hainan Province,Haikou 570311,China 【Abstrat】 Purpose: To evaluate the efficacy of Chinese traditional medicine compound xuanju capsule in the treatment of inferiticity caused by subclinnical varicocele(SVC).Methods:62 patients with male inferticity caused by subclinical varicocele were diagnosed by Doppler Sonography and Semen quality analysis ,and were treated with compound xuanju capsule 1.26g three times one day for 3 mounths.Results:A total of 58 patients accomplished the clinical trial.32 patients was left SVC,6 patients was right SVC, and 20 patients was double SVC.The sperm density and seminal plasma fructose level of singal SVC group were significantly improved after 12 weeks of Fufang Xuanju treatment（P＜0.05）, the difference between 6 weeks of treatment and Pre-treament was not significant.sperm vitality, motility(a+b),the zinc and alpha-glucosidase level in seminal plasma were significantly improved after 6 weeks and 12 weeks treatment（P＜0.05）. the zinc level in seminal plasma of double SVC patients were significantly improved after 6 weeks and 12 weeks treatment（P＜0.05).sperm vitality, motility(a+b