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脸红不宜喝酒的原因(Reasons for blushing)
脸红不宜喝酒的原因(Reasons for blushing)
Rumor: about 1/3 of East Asians drink red, a symptom known as Asian Flush, which increases the risk of fatal esophageal cancer. Drinking blush responders because of the alcohol metabolism enzyme ALDH2 gene defects, not to acetaldehyde metabolism into acetate, resulting in a toxic acetaldehyde accumulation in the body, causing vasodilation caused by reaction. ~ ~ ~ dont try to be brave, after drink or not drink, resolutely not cancer! Truth: in the rumor, the phenomenon of redness of the face and upper body soon after drinking.
Because it happens to people in Asia, it is called Asian Flush, also known as Asian Red or Asian Glow. But many people think that this is allergic to alcohol reaction, often to be careless with drink, or try to eat allergy medicine to relieve. In fact, this has nothing to do with allergies. It is the accumulation of acetaldehyde produced by alcohol metabolism in the body. When alcohol is used to metabolize alcohol, the alcohol is absorbed into the bloodstream in the digestive tract. In addition to less than 10% of the amount of alcohol is excreted by ethanol, Haragata Yu and kidneys, the major metabolic occurs in the liver.
In simple terms, alcohol is first catalyzed by alcohol dehydrogenase (ADH) to metabolize acetaldehyde. Acetaldehyde is further converted into acetic acid under the action of aldehyde dehydrogenase 2 (ALDH2). Acetic acid is involved in multiple metabolic pathways in the body, and finally CO2 and water are removed. Among them, in addition to ethanol itself has a certain toxicity, the most dangerous is acetaldehyde, and many tissues and organs are toxic, may cause DNA damage, is also considered a variety of carcinogenic effects. In animal experiments, or even using acetaldehyde as a mutagen for cancer models. Visible, if the accumulation of acetaldehyde in the body, is very detrimental to health. The export of acetaldehyde is metabolic by ALDH2, so if the action of ALDH2 is a problem, acetaldehy
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