海绵硅蛋白研究进展.PDF

生 物 工 程 学 报 Chin J Biotech 2009, December 25; 25(12): 1882-1886 journals.im.ac.cn Chinese Journal of Biotechnology ISSN 1000-3061 cjb@im.ac.cn © 2009 Institute of Microbiology, CAS CSM, All rights reserved 综 述 1 1,2 1 1,3 曹旭鹏 , 曹恒 , 虞星炬 , 张卫 1 , 116023 2 , 100049 3 Flinders , SA5042 : 海绵是生物进化过程中最古老的多细胞动物, 其中大部分能够利用二氧化硅在常温水环境下合成形状、大小和 结构极为丰富的硅质骨骼。随着近年来人们发现其骨骼的基本组成单位骨针具有优异的光导性能和机械性能, 海绵生物 硅化过程及仿生纳米和微米硅质生物材料合成的研究成为生物技术和材料科学的热点。在海绵生物硅化过程中, 一类被 称为硅蛋白(Silicatein)的蛋白质表现出了特殊的催化活性, 也因此得到了生物学家、化学家和材料学家的关注。以下将 对硅蛋白的国际研究现状进行了评述, 以期促进国内相关领域的研究。 : 海绵硅质骨针, 硅蛋白, 生物硅化, 生物硅质材料 Progress in silicatein from sponges 1 1,2 1 1,3 Xupeng Cao , Heng Cao , Xingju Yu , and Wei Zhang 1 Marine Bioproducts Engineering Group , Dalian Institute of Chemical Physics , Chinese Academic of Sciences, Dalian 116023, China 2 Graduate School of the Chinese Academy of Sciences, Beijing 100049, China 3 Flinders Centre for Marine Bioprocessing and Bioproducts, Flinders University, Adelaide SA5042, Australia Abstract: Sponges (Porifera) are the oldest living metazoan in the world, among which most of them (Demospongia) can produce silicic skeleton from orthosilicic acid in the seawater under the natural environmental conditions. These biosilicic materials exhibit good mechanical and optical properties as well as good biocompatibility. During the biosilicification process of sponges, a protein, named as silicatein, plays an important role and