NDGA对HT-29结肠癌细胞诱导凋亡、凋亡机制及对其转移影响地研究.pdf

oN RESEARCHNDGA’SINDUCINGAPoPTOSISOF CoLoNCANCERCELLLINE oFTHISAPoPTOSISANDINFLUENCEoN ITSMETASTASIS DoctoralStudent：Xia Guangtao Tutor：Professor ZhangShangzhong ABSTRACT cancerisa commonkindof Background：Colon malignant tothe like of tumor．Duefactorsthe improvementpeople’sliving standard，theoffatcontentin diet，the increasing people’s everyday in incidencerateofthisdieaseisontherise recent years．The is andmetastasisis seenin age gradually episode declining easily from ofitinclude earlystage．Apartsurgicaloperation，treatments and effectsof traditional radiotherapy．However，the chemotherapy suchas5-FU chemothe are too rapydrugs unsatisfying，withmany side—effectsand toleranceof are poor in new now an effectivetotreat vigorouslyengagedseeking drug callCer． colon Thefocusof or onthe research，domesticabroad，is ofarachidoni