慢性应激对小鼠神经免疫内分泌功能影响及药物干预作用.pdf

慢性应激对小鼠神经免疫内分泌功能影响及药物干预作用.pdf

!璺堡塑堕型查登堡主堂垡堡兰 stress and interferencewhichwas group, drug subdividedinto group pure garlicpowder of group,high,moderat。andl。岬dosagetyrosinegroHp.After submittedtochronicand stressforfourcontinuOusthe unpredictable weeks, mOdelwas identifiedassuccessfulornot actionstest byspontaneous and Morris watermazetest.罩henweobservedof 8nd changesweightorgans(spleen, and adrenal indicesofthemiceandevaluatedendocrine thymus gland) functions their1eve】sofseraand bydetermining TT3 TT“In ini瞅munitiesofthe珥odelanimalswereexaminedlcells and by prolifer8tion test.Andat thecontentmeasurementsof killing last, inbrainwere tofurtherestimatethe of Dopamine(DA) employed impairment chronicand stresstothenervousandtheeffectof unpredictable system drug interferenco. Results: l+Afterehronicand stressfor unpredictablefourcontinuousweeks,theweight ofthe submitted tOstressincreasedwiththe fourweeks group compared weight withthenormal no before(尺O。01).HoWever,Comparedcontr01,significant differencew8s observed(respectively,.乃O.05)+ 2. withthenormal behaviorsto8 novel Co叩ared contr01,exploring environmentand actionstoan ind

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