丹参红花配伍研究进展.PDFVIP

中草药 Chinese Traditional and Herbal Drugs 第 47 卷 第 4 期 2016 年 2 月 ·671 · ·综 述· 丹参红花配伍研究进展 1, 2 1, 2* 1, 2 1, 2 高丽娜 ，崔元璐 ，延 阔 ，邱 超 1. 天津中医药大学中医药研究院，天津 300193 2. 天津市现代中药重点实验室，天津 300193 摘 要：丹参和红花是近代中药方剂中的常见药对配伍，两药均为活血化瘀常用药，历经几百年临床用药的验证，沿用至今， 经久不衰。目前，已有很多上市的丹参红花配伍使用的中成药制剂。综述了丹参红花复方制剂、药对配伍和组分配伍的研究 现状，阐明丹参红花配伍前后的化学成分、药理作用、药效物质基础以及药动学研究进展，并指明其配伍使用的科学性和必 要性，为丹参红花配伍的深入研究与现代制剂开发提供参考。 关键词：丹参；红花；配伍；药对；药效物质基础 中图分类号：R284 ；R285 文献标志码：A 文章编号：0253 - 2670(2016)04 - 0671 - 09 DOI: 10.7501/j.issn.0253-2670.2016.04.024 Advances in studies on compatibility of Salviae Miltiorrhizae Radix et Rhizoma and Carthamii Flos GAO Li-na1, 2, CUI Yuan-lu1, 2, YAN Kuo1, 2, QIU Chao1, 2 1. Research Center of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 2. Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China Abstract: The compatibility of Salviae Miltiorrhizae Radix et Rhizoma (SMRR) and Carthamii Flos (CF) is a common pair-herb used in the modern traditional Chinese medicine prescriptions. As a function of promoting blood circulation and removing blood stasis, both SMRR and CF have been clinically used for hundreds of years and enduring popularity until today. At present, there have been many listed Chinese medicine prescriptions which were compatible with SMRR and CF. In this paper, we reviewed the research status of the formulae preparations, pair-herb compatibility, and component compatibility of SMRR and CF. We clarified the research advances in the chemistry, pharmacology, effective material base, and pharmacokinetics before and after the compatibility of SMRR and CF. Further, we indicated the scientificity and necessity of its compatibility and provided th