大叶醉鱼草化学成分的提取、分离、纯化研究1.docVIP

大叶醉鱼草化学成分提取、分离、纯化研究 摘 要 Buddleia davidii）属于马钱科醉鱼草属（Buddleja L．）。醉鱼草属植物中有很多种类由于形态优美、叶片对称和芳香宜人，因此是极具开发价值的园林植物，可用于园林绿化、室内观赏。现在许多国家已将醉鱼草属观赏植物运用于商业，利用高科技培育了许多比野生种更美的栽培品种，其中大叶醉鱼草是研究开发利用最为深入的种类。它贵阳、遵义、六盘水安顺苯乙醇苷类1H-NMR、13C-NMR、1H -1H COSY等现代波谱方法分离、鉴定得到了两个化合物，分别为：木樨草素和金合欢素-7-O-芸香糖苷。 关键词：, 金合欢素-7-O-芸香糖苷 Abstract Buddleia davidii is one of Buddleja L..Because of many kinds of Genus Buddleja have beautiful shape, symmetry leaves and fragrant, they are of great value garden plants, which can be used for landscaping and indoor ornamental. Now Buddleja Plants have been used in business in many countries. People use high-tech training a lot of species more beautiful than the wild cultivars, which the Buddleia davidii is the most in-depth research and development of the type of use. It is mainly distributed in the Yangtze River basin, and distributed in Guiyang, Zunyi, Liupanshui, Bijie and Anshun and other places in Guizhou. In medicine Buddleia davidii are used to treat rheumatic joint pain, bruises, and influenza. Some places even use it to treat skin diseases and burns roots. There have been reported the chemical constituents of Buddleia davidii. Through these reports we found that this plant mainly contains flavonoids, phenyl glycosides, lignin, terpenoids and other compounds, These results for studying, developing and using Buddleia davidii, and for studying the bioactivities of Buddleia davidii provides relevant theoretical basis. In the study, using Silica gel column chromatography, gel column chromatography, poly- amide column chromatography, macroporous resin, reverse phase separation of silica and other means of separation, single compounds were obtained. And comprehensive utilization of IR, UV, MS, 1H-NMR, 13C-NMR, 1H -1H COSY spectrum of modern methods, separated and identified two compounds, they are luteolin and acacetin-7-O-α-L-rhamnopyranosyl-(1-6 )-β-D-glucopyranoside . Keywords: Buddleja davidii, Chemical Constituents, Luteolin,