MR医学影像文献Zhou-2016-Characterization of Compacted Myocar.pdfVIP

1210 ZHOU H et al. Circulation Journal ORIGINAL ARTICLE Official Journal of the Japanese Circulation Society http://www.j-circ.or.jp Imaging Characterization of Compacted Myocardial Abnormalities by Cardiac Magnetic Resonance With Native T1 Mapping in Left Ventricular Non-Compaction Patients – A Comparison With Late Gadolinium Enhancement – Hongmei Zhou, MD; Xue Lin, MD, PhD; Ligang Fang, MD, PhD; Xihai Zhao, MD, PhD; Haiyan Ding, PhD; Wei Chen, MD, PhD; Ruiyi Xu, MD, PhD; Xiaoyin Bai, MD; Yining Wang, MD; Quan Fang, MD, PhD Background: Native T1 mapping is an emerging cardiac magnetic resonance technique for quantitative evaluation of cardiomyopathies. This study aimed to investigate the usefulness of native T1 mapping in characterizing myocar- dial abnormalities in left ventricular non-compaction (LVNC) by comparing it with late gadolinium enhancement (LGE). Methods and Results: The study group of 31 LVNC patients and 8 normal controls underwent cardiovascular magnetic resonance to acquire the native T1 maps and LGE images. Of the 31 LVNC patients, 14 had LGE. The mean native T1 value of the normal controls, LGE(−) and LGE(+) patients was 1,098.8±40.8 ms, 1140.6±32.8 ms, and 1181.4±53.7 ms, respectively. Significant differences were found in native T1 between any 2 groups (F=9.74, P0.001). In discriminating the presence of LGE in LVNC patients, the odds ratio and corresponding 95% confidence interv