老年高血压降压指南.ppt

从HYVET到 2008年中国老年高血压治疗指南;;Treatment better;Western Europe(86) Easter Europe(2144) China(1526)Astrania(19) Tunisia(70); Inclusion criteria: 　exclusion criteria: Aged 80 or more， standing SBP 140mmHg systolic pressure：160 -199mmHg Stroke in last 6 months diastolic pressure110 mmHg，　　　　 dementia informed consent required ongoing nursing care primary outcome： Stroke events (Fatal and non fatal);;Time of Follow-up（year）;;P=0.046;P0.0001;placebo;HYVET: Safety;HYVET: 意义;;从HYVET到临床实践 ;HOT-CHINA;老年高血压的诊断与治疗2008中国专家共识要点(全文刊登在中华内科杂志2008年47卷第12期1046-1050);2. 老年高血压的治疗策略;3: 老年高血压合并其他疾病时的降压目标及药物选择;;4 高龄老年高血压患者降压治疗的循证医学证据及治疗建议;总 结;问 题;回 答;;Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial: The Telmisartan trial in cardiovascular protection;ONTARGET Study Design;Possible results for the end of the Trial for ONTARGET Non-Inferiority Comparison;ONTARGET: Key Baseline Characteristics;ONTARGET: Change in BP (mmHg);Time to Primary Outcome;ONTARGET: Primary Outcome  HOPE Primary Outcome;非劣势比较(Non-Inferiority Comparison) Tel vs. Ram;ONTARGET Non-Inferiority Comparison;Indirect Comparison of Telmisartan to Placebo Percentage of Ramipril’s Effects That is Preserved;Reasons for Permanently Stopping Study MedicationsTel vs. Ram;优势比较(superiority Comparison)Tel + Ram vs. Ram;Reasons for Permanently Stopping Study MedicationsTel + Ram vs. Ram;Renal Dysfunction Dialysis Related DeathTel + Ram vs. Ram;临床意义(一); 冠心病(%) 79.5 74.5 既往心肌梗死(%) 51.9 49.3 心绞痛(%) 54.9 49.8 既往CABG(%) 25.7 22.5 既往PTCA(%) 18.4 29.0 脑卒中/TIA(%) 10.8 20.6 外周血管病(%) 42.3 13.6 ECG-LVH(%) 8.2 13.1 高血压(%) 47.6 68.6 糖尿病(%) 38.9 38.0 MAU(%) 20.5 13.2; ; ;临床意义(二);