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芍甘口服液提取、精制工艺线路设计.docx

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目录1. 设计任务书························································042. 设计概述···························································05 2.1 绪论································································05 2.1.1芍药甘草汤概述··············································05 2.2 工艺选择··························································· 06 2.2.1提取工艺·······················································062.2.2 精制工艺······················································062.2.2.1常用技术·················································072.2.2.2超滤技术·················································082.3课程实验····························································102.3.1 实验目的······················································102.3.2 仪器与试剂···················································102.3.3 实验内容······················································102.3.4实验结果与讨论··············································112.3.5数据分析····················································· 13 2.4 参数确定···························································14 2.5工艺线路设计······················································142.6工艺线路····························································152.6.1提取与精制工艺··············································162.6.2成型工艺·······················································172.6.3生产数据表····················································173. 心得体会······························································184.参考文献······························································18设计任务书（一）一、设计题目芍甘汤提取、精制工艺设计（按随机抽签，确定小组设计题目）二、设计条件（1）芍甘复方颗粒剂提取物二、设计内容与要求（1）确定提取工艺及参数；（2）确定精制分离工艺及参数；（3）提取物得率、成分含量以及相对密度；（5）编写设计说明书；三、设计成果（1）设计说明书一份包括概述（简要说明所设计的复方中药效物质成分类型、性质及药理作用等）；常用精制分离技术简述（主要为高速离心、醇沉、大孔树脂吸附以及超滤）课程实验（不同精制方法的效果及比较）；工艺线路的设计（从最终制剂的剂型、工艺合理性以及生产成本等方面考虑）。（2）芍甘汤提取精制工艺流程图；四、设计时间设计时间为2周，从2013年5月12日至2013年5月23日。（二）设计概述2.1绪论2.1.1芍药甘草汤概述：◆芍药甘草汤【来源】《伤寒论》。【异名】戊己汤(《症因脉治》卷四)。【组成】芍药12克甘草12克【用法】上二味，用水600毫升，煮取300毫升，去滓，分温再服。【功用】调和肝脾，缓急止痛。【主治】伤寒伤阴，筋脉失濡，腿脚挛急，心烦，微恶寒，肝