芳基噻二唑类化合物的合成.docVIP

芳基噻二唑类化合物的合成 摘要： 噻二唑类化合物因其广泛的应用已被越来越多的关注。其应用范围涵盖了工业，农业，医药业等重要行业。含有3个杂原子的1,3,4-噻二唑衍生物是一类重要的杂环化合物,因该类化合物具N-C-S毒性基而具有广谱生物活性, 目前已经被广泛应用。论文将采用取代苯甲酸和氨基硫脲为原料，在三氯氧磷的催化作用下，合成制备系列取代苯基噻二唑，分离、提纯并进行结构表征。 关键词: 1,3,4-噻二唑 合成 Abstract Thiadiazole compounds because of its wide range of applications has been more and more attention. Its scope of application covers industry,agriculture,pharmaceuticals and other important sectors.3 heteroatom containing 1,3,4-thiadiazole derivatives are an important class of heterocyclic compounds, with N-C-S due to toxicity of these compounds have a broad spectru